Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014251..2014396 Replicon chromosome
Accession NZ_CP101784
Organism Klebsiella pneumoniae strain hvKP841

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014287..2014389 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014251..2014396 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPJ85_RS09885 (NPJ85_09885) 2009381..2011441 + 2061 WP_004151449.1 oligopeptidase B -
NPJ85_RS09890 (NPJ85_09890) 2011445..2012104 - 660 WP_002911407.1 exodeoxyribonuclease X -
NPJ85_RS09895 (NPJ85_09895) 2012183..2012413 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NPJ85_RS09900 (NPJ85_09900) 2012526..2012900 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NPJ85_RS09905 (NPJ85_09905) 2012904..2013773 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NPJ85_RS09910 (NPJ85_09910) 2013790..2014128 + 339 WP_002911404.1 YebY family protein -
- 2014251..2014396 - 146 - - Antitoxin
- 2014287..2014389 + 103 - - Toxin
NPJ85_RS09915 (NPJ85_09915) 2014764..2014907 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NPJ85_RS09920 (NPJ85_09920) 2015012..2015980 - 969 WP_004151446.1 VirK/YbjX family protein -
NPJ85_RS09925 (NPJ85_09925) 2016137..2016790 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NPJ85_RS09930 (NPJ85_09930) 2016787..2016978 - 192 WP_002911395.1 YebW family protein -
NPJ85_RS09935 (NPJ85_09935) 2017076..2017315 - 240 WP_002911393.1 YebV family protein -
NPJ85_RS09940 (NPJ85_09940) 2017431..2018864 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252696 NZ_CP101784:2014287-2014389 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252696 NZ_CP101784:c2014396-2014251 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References