Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2015557..2015702 | Replicon | chromosome |
| Accession | NZ_CP101776 | ||
| Organism | Klebsiella pneumoniae strain hvKP340 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2015593..2015695 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2015557..2015702 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NPJ84_RS09900 (NPJ84_09900) | 2010687..2012747 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NPJ84_RS09905 (NPJ84_09905) | 2012751..2013410 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NPJ84_RS09910 (NPJ84_09910) | 2013489..2013719 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NPJ84_RS09915 (NPJ84_09915) | 2013832..2014206 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NPJ84_RS09920 (NPJ84_09920) | 2014210..2015079 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| NPJ84_RS09925 (NPJ84_09925) | 2015096..2015434 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2015557..2015702 | - | 146 | - | - | Antitoxin |
| - | 2015593..2015695 | + | 103 | - | - | Toxin |
| NPJ84_RS09930 (NPJ84_09930) | 2016070..2016213 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NPJ84_RS09935 (NPJ84_09935) | 2016318..2017286 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NPJ84_RS09940 (NPJ84_09940) | 2017443..2018096 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NPJ84_RS09945 (NPJ84_09945) | 2018093..2018284 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NPJ84_RS09950 (NPJ84_09950) | 2018382..2018621 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NPJ84_RS09955 (NPJ84_09955) | 2018737..2020170 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T252670 NZ_CP101776:2015593-2015695 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT252670 NZ_CP101776:c2015702-2015557 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
