Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1991228..1991373 Replicon chromosome
Accession NZ_CP101770
Organism Klebsiella pneumoniae strain hvKP323

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1991264..1991366 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1991228..1991373 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO368_RS09765 (NO368_09765) 1986358..1988418 + 2061 WP_004151449.1 oligopeptidase B -
NO368_RS09770 (NO368_09770) 1988422..1989081 - 660 WP_002911407.1 exodeoxyribonuclease X -
NO368_RS09775 (NO368_09775) 1989160..1989390 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NO368_RS09780 (NO368_09780) 1989503..1989877 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NO368_RS09785 (NO368_09785) 1989881..1990750 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NO368_RS09790 (NO368_09790) 1990767..1991105 + 339 WP_002911404.1 YebY family protein -
- 1991228..1991373 - 146 - - Antitoxin
- 1991264..1991366 + 103 - - Toxin
NO368_RS09795 (NO368_09795) 1991741..1991884 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NO368_RS09800 (NO368_09800) 1991989..1992957 - 969 WP_004151446.1 VirK/YbjX family protein -
NO368_RS09805 (NO368_09805) 1993114..1993767 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NO368_RS09810 (NO368_09810) 1993764..1993955 - 192 WP_002911395.1 YebW family protein -
NO368_RS09815 (NO368_09815) 1994053..1994292 - 240 WP_002911393.1 YebV family protein -
NO368_RS09820 (NO368_09820) 1994408..1995841 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252645 NZ_CP101770:1991264-1991366 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252645 NZ_CP101770:c1991373-1991228 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References