Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008471..2008616 Replicon chromosome
Accession NZ_CP101764
Organism Klebsiella pneumoniae strain hvKP319

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008507..2008609 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008471..2008616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPJ83_RS09845 (NPJ83_09845) 2003601..2005661 + 2061 WP_004151449.1 oligopeptidase B -
NPJ83_RS09850 (NPJ83_09850) 2005665..2006324 - 660 WP_002911407.1 exodeoxyribonuclease X -
NPJ83_RS09855 (NPJ83_09855) 2006403..2006633 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NPJ83_RS09860 (NPJ83_09860) 2006746..2007120 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NPJ83_RS09865 (NPJ83_09865) 2007124..2007993 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NPJ83_RS09870 (NPJ83_09870) 2008010..2008348 + 339 WP_002911404.1 YebY family protein -
- 2008471..2008616 - 146 - - Antitoxin
- 2008507..2008609 + 103 - - Toxin
NPJ83_RS09875 (NPJ83_09875) 2008984..2009127 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NPJ83_RS09880 (NPJ83_09880) 2009232..2010200 - 969 WP_004151446.1 VirK/YbjX family protein -
NPJ83_RS09885 (NPJ83_09885) 2010357..2011010 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NPJ83_RS09890 (NPJ83_09890) 2011007..2011198 - 192 WP_002911395.1 YebW family protein -
NPJ83_RS09895 (NPJ83_09895) 2011296..2011535 - 240 WP_002911393.1 YebV family protein -
NPJ83_RS09900 (NPJ83_09900) 2011651..2013084 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252613 NZ_CP101764:2008507-2008609 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252613 NZ_CP101764:c2008616-2008471 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References