Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 5336493..5337632 | Replicon | chromosome |
| Accession | NZ_CP101752 | ||
| Organism | Pseudomonas citronellolis strain C12 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A1A9KFP9 |
| Locus tag | NOX82_RS23320 | Protein ID | WP_009620578.1 |
| Coordinates | 5336493..5337263 (-) | Length | 257 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A1A5D9R9 |
| Locus tag | NOX82_RS23325 | Protein ID | WP_043271094.1 |
| Coordinates | 5337264..5337632 (-) | Length | 123 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NOX82_RS23305 (NOX82_23305) | 5333150..5334037 | + | 888 | WP_009620572.1 | metal-dependent hydrolase | - |
| NOX82_RS23310 (NOX82_23310) | 5334323..5335687 | - | 1365 | WP_116423183.1 | DNA recombination protein RmuC | - |
| NOX82_RS23315 (NOX82_23315) | 5336211..5336417 | - | 207 | WP_256512291.1 | hypothetical protein | - |
| NOX82_RS23320 (NOX82_23320) | 5336493..5337263 | - | 771 | WP_009620578.1 | RES family NAD+ phosphorylase | Toxin |
| NOX82_RS23325 (NOX82_23325) | 5337264..5337632 | - | 369 | WP_043271094.1 | DUF2384 domain-containing protein | Antitoxin |
| NOX82_RS23330 (NOX82_23330) | 5337911..5338345 | + | 435 | WP_074981540.1 | RcnB family protein | - |
| NOX82_RS23335 (NOX82_23335) | 5338352..5338783 | - | 432 | WP_064583930.1 | hypothetical protein | - |
| NOX82_RS23340 (NOX82_23340) | 5338912..5339394 | + | 483 | WP_253392323.1 | GreA/GreB family elongation factor | - |
| NOX82_RS23345 (NOX82_23345) | 5339466..5339807 | + | 342 | WP_009620588.1 | carboxymuconolactone decarboxylase family protein | - |
| NOX82_RS23350 (NOX82_23350) | 5339899..5340270 | + | 372 | WP_116423096.1 | hypothetical protein | - |
| NOX82_RS23355 (NOX82_23355) | 5340258..5341307 | - | 1050 | WP_116423095.1 | diguanylate cyclase | - |
| NOX82_RS23360 (NOX82_23360) | 5341601..5342437 | + | 837 | WP_116423094.1 | 5'-nucleotidase, lipoprotein e(P4) family | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 257 a.a. Molecular weight: 28862.03 Da Isoelectric Point: 7.0428
>T252604 WP_009620578.1 NZ_CP101752:c5337263-5336493 [Pseudomonas citronellolis]
MALDAGAELWRECRGEQAIAPLRGKLVRLVESQEQVATLQLVDTLEEQALLEELIETSKPHLPPSTETLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALRLETAMAEAAYYRFVLWEGMASPPPSGRILSEHASFEARFQVQRGIRLQAPPFDSYAER
LQDPRDYRLTQALGSAMRAAAVEAFEYRSARCPEGGLNAALFVPSAFVDKRPRNLMPWLCETTADYVAFKHAQVPGAPRL
FPRAGFLVEGDLPHPA
MALDAGAELWRECRGEQAIAPLRGKLVRLVESQEQVATLQLVDTLEEQALLEELIETSKPHLPPSTETLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALRLETAMAEAAYYRFVLWEGMASPPPSGRILSEHASFEARFQVQRGIRLQAPPFDSYAER
LQDPRDYRLTQALGSAMRAAAVEAFEYRSARCPEGGLNAALFVPSAFVDKRPRNLMPWLCETTADYVAFKHAQVPGAPRL
FPRAGFLVEGDLPHPA
Download Length: 771 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13395.70 Da Isoelectric Point: 10.8284
>AT252604 WP_043271094.1 NZ_CP101752:c5337632-5337264 [Pseudomonas citronellolis]
MSALIRETPSADLVLAKAVLAAREQLGMTQQELAAIVGVDRSAVSRWKSGGLRVGSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTPNRHLSGVPLQRMEQVQGLVQVVEYLDAIRGKI
MSALIRETPSADLVLAKAVLAAREQLGMTQQELAAIVGVDRSAVSRWKSGGLRVGSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTPNRHLSGVPLQRMEQVQGLVQVVEYLDAIRGKI
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1A9KFP9 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1A5D9R9 |