Detailed information of TA system TA252603

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 5323146..5324585
• Replicon: chromosome
• Accession: NZ_CP101752
• Organism: Pseudomonas citronellolis strain C12

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NOX82_RS23280
• Protein ID: WP_116423104.1
• Coordinates: 5324016..5324585 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NOX82_RS23275
• Protein ID: WP_256512281.1
• Coordinates: 5323146..5324006 (-)
• Length: 287 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NOX82_RS23255 (NOX82_23255)	5318687..5319631	+	945	WP_116423107.1	bile acid:sodium symporter family protein	-
NOX82_RS23260 (NOX82_23260)	5319775..5320089	+	315	WP_009620556.1	quaternary ammonium compound efflux SMR transporter SugE	-
NOX82_RS23265 (NOX82_23265)	5320281..5320490	+	210	WP_009620558.1	cold-shock protein	-
NOX82_RS23270 (NOX82_23270)	5320540..5322414	-	1875	WP_256512280.1	MFS transporter	-
NOX82_RS23275 (NOX82_23275)	5323146..5324006	-	861	WP_256512281.1	AraC family transcriptional regulator	Antitoxin
NOX82_RS23280 (NOX82_23280)	5324016..5324585	-	570	WP_116423104.1	GNAT family protein	Toxin
NOX82_RS23285 (NOX82_23285)	5324837..5328313	+	3477	WP_256512284.1	hybrid sensor histidine kinase/response regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (197-273)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21092.38 Da
• Isoelectric Point: 10.2630

>T252603 WP_116423104.1 NZ_CP101752:c5324585-5324016 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALRFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDSVLYSITDLEWPQVKAALEAGFIG

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 287 a.a.
• Molecular weight: 31642.00 Da
• Isoelectric Point: 8.7317

>AT252603 WP_256512281.1 NZ_CP101752:c5324006-5323146 [Pseudomonas citronellolis]
MPLDSAHGERTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIGQVGSVLDELELGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWRETLLLLFQR
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRLACGRSGLSPGNL

Nucleotide

• Length: 861 bp