Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 3069734..3070322 Replicon chromosome
Accession NZ_CP101752
Organism Pseudomonas citronellolis strain C12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NOX82_RS13815 Protein ID WP_083426757.1
Coordinates 3069734..3070084 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Z0IXF0
Locus tag NOX82_RS13820 Protein ID WP_074979635.1
Coordinates 3070065..3070322 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOX82_RS13790 (NOX82_13790) 3066115..3066861 + 747 WP_253390768.1 glucose 1-dehydrogenase -
NOX82_RS13795 (NOX82_13795) 3066896..3067855 + 960 WP_253390769.1 VOC family protein -
NOX82_RS13800 (NOX82_13800) 3067852..3068688 + 837 WP_253411361.1 alpha/beta fold hydrolase -
NOX82_RS13805 (NOX82_13805) 3068693..3069118 + 426 WP_009619921.1 lipocalin-like domain-containing protein -
NOX82_RS13815 (NOX82_13815) 3069734..3070084 - 351 WP_083426757.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NOX82_RS13820 (NOX82_13820) 3070065..3070322 - 258 WP_074979635.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NOX82_RS13825 (NOX82_13825) 3070830..3071180 - 351 WP_009619928.1 hypothetical protein -
NOX82_RS13830 (NOX82_13830) 3071612..3072037 + 426 WP_074979636.1 hydrogenase -
NOX82_RS13835 (NOX82_13835) 3072343..3072762 - 420 WP_256515078.1 LytTR family DNA-binding domain-containing protein -
NOX82_RS13845 (NOX82_13845) 3073455..3073670 + 216 WP_009619935.1 hypothetical protein -
NOX82_RS13850 (NOX82_13850) 3073797..3074015 - 219 WP_009619937.1 hypothetical protein -
NOX82_RS13855 (NOX82_13855) 3074159..3074536 + 378 WP_256515079.1 S24 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(26-105)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13484.56 Da        Isoelectric Point: 10.5002

>T252600 WP_083426757.1 NZ_CP101752:c3070084-3069734 [Pseudomonas citronellolis]
MTSKTGNNKQIKAPQQDLEDIKQYTLKFKETALKEWDRLKGPVKTQLIKKLGERLVNPRVEKDKLHGSENKDRYKIKLSA
SGYRLVYQVHDTEIVVEVVAVGKRERSAVYNESKKR

Download         Length: 351 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9373.65 Da        Isoelectric Point: 4.3516

>AT252600 WP_074979635.1 NZ_CP101752:c3070322-3070065 [Pseudomonas citronellolis]
MPHALLADVTASITELKKDPMGTVGAGMGHAVAILNRNEPVFYAVPADEYERMIELLDDIYLGRLADERKDESSVTVSLD
DLKNR

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A4Z0IXF0

References