Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 821392..823054 Replicon chromosome
Accession NZ_CP101752
Organism Pseudomonas citronellolis strain C12

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag NOX82_RS03790 Protein ID WP_256514149.1
Coordinates 822218..823054 (-) Length 279 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag NOX82_RS03785 Protein ID WP_058071792.1
Coordinates 821392..822213 (-) Length 274 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOX82_RS03765 (NOX82_03765) 816611..818098 - 1488 WP_256514144.1 aldehyde dehydrogenase -
NOX82_RS03770 (NOX82_03770) 818109..818912 - 804 WP_256514145.1 aspartate dehydrogenase -
NOX82_RS03775 (NOX82_03775) 818923..820605 - 1683 WP_256514146.1 thiamine pyrophosphate-binding protein -
NOX82_RS03780 (NOX82_03780) 820598..821395 - 798 WP_256514147.1 SDR family oxidoreductase -
NOX82_RS03785 (NOX82_03785) 821392..822213 - 822 WP_058071792.1 IclR family transcriptional regulator Antitoxin
NOX82_RS03790 (NOX82_03790) 822218..823054 - 837 WP_256514149.1 alpha/beta fold hydrolase Toxin
NOX82_RS03795 (NOX82_03795) 823074..823607 - 534 WP_116426055.1 cupin domain-containing protein -
NOX82_RS03800 (NOX82_03800) 823619..824380 - 762 WP_256514150.1 SDR family oxidoreductase -
NOX82_RS03805 (NOX82_03805) 824391..825164 - 774 WP_043315312.1 ABC transporter permease -
NOX82_RS03810 (NOX82_03810) 825181..826179 - 999 WP_074986021.1 ABC transporter substrate-binding protein -
NOX82_RS03815 (NOX82_03815) 826200..827042 - 843 WP_116426052.1 ABC transporter ATP-binding protein -
NOX82_RS03820 (NOX82_03820) 827487..827639 - 153 WP_256514152.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(40-268)

Antitoxin

Transcription regulator IclR, C-terminal

(133-254)


Sequences

Toxin        


Download         Length: 279 a.a.        Molecular weight: 29482.01 Da        Isoelectric Point: 7.2820

>T252596 WP_256514149.1 NZ_CP101752:c823054-822218 [Pseudomonas citronellolis]
MSTAAAWQADLERDFPQRLVRRGEVVSAWREAGAADAPALVLLHGIGSGAASWLLLAQCLKARARLIAWDAPGYGESTPL
AEAAPRAEAYMQRLRELLDALDVQRCVLLGHSLGALTALALANAEPRRVARLLLLSPARGYGARPAEGEAVRSRRLAGLA
SEGIAGLAERRAPAMLSASPGAEALAWVRWNMARLKPHGYRQAVELLCGDDLLRLGRPPVPVEVLCGSEDGITPPAACRE
VAETLAAPFQLVPGAGHASPIECPEALAGHLVRFLDKD

Download         Length: 837 bp

Antitoxin


Download         Length: 274 a.a.        Molecular weight: 30315.89 Da        Isoelectric Point: 6.7546

>AT252596 WP_058071792.1 NZ_CP101752:c822213-821392 [Pseudomonas citronellolis]
MSTDTLTENQERYMVPGLERGLTLLGEFTRHDRTLTAPELARRLQLPRTTIFRLLATLEALGFVTRSGNEYRLGMAVLRL
GFEYLASLELTELGQPILRRLCDAIGYSCNLVVRDGRNIVYVAKISPPSILTSAVNVGTRLPAHATVLGRILLEDLDLAA
LRELYPEKQLERFSEGTPRSTEELFDLVQNDRLRGYALSEGFFEASISTVAAPVRDHTGRVCAAMGVTIPATRIAEHLLE
PLVRQVRNSAEELSGLLGHMPNPNVLSLQRVHS

Download         Length: 822 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References