Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2030133..2030278 Replicon chromosome
Accession NZ_CP101726
Organism Klebsiella pneumoniae strain 150040X1B1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2030169..2030271 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2030133..2030278 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPN21_RS09955 (NPN21_09955) 2025263..2027323 + 2061 WP_004151449.1 oligopeptidase B -
NPN21_RS09960 (NPN21_09960) 2027327..2027986 - 660 WP_002911407.1 exodeoxyribonuclease X -
NPN21_RS09965 (NPN21_09965) 2028065..2028295 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NPN21_RS09970 (NPN21_09970) 2028408..2028782 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NPN21_RS09975 (NPN21_09975) 2028786..2029655 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NPN21_RS09980 (NPN21_09980) 2029672..2030010 + 339 WP_002911404.1 YebY family protein -
- 2030133..2030278 - 146 - - Antitoxin
- 2030169..2030271 + 103 - - Toxin
NPN21_RS09985 (NPN21_09985) 2030646..2030789 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NPN21_RS09990 (NPN21_09990) 2030894..2031862 - 969 WP_004151446.1 VirK/YbjX family protein -
NPN21_RS09995 (NPN21_09995) 2032019..2032672 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NPN21_RS10000 (NPN21_10000) 2032669..2032860 - 192 WP_002911395.1 YebW family protein -
NPN21_RS10005 (NPN21_10005) 2032958..2033197 - 240 WP_002911393.1 YebV family protein -
NPN21_RS10010 (NPN21_10010) 2033313..2034746 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252556 NZ_CP101726:2030169-2030271 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252556 NZ_CP101726:c2030278-2030133 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References