Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2135882..2136153 Replicon chromosome
Accession NZ_CP101705
Organism Escherichia coli strain 035152

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2136012..2136115 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2135882..2136153 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPL72_RS10290 2132437..2133099 - 663 WP_000944256.1 exodeoxyribonuclease X -
NPL72_RS10295 2133123..2133779 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NPL72_RS10300 2133881..2134111 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NPL72_RS10305 2134250..2134624 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NPL72_RS10310 2134628..2135500 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
NPL72_RS10315 2135513..2135854 + 342 WP_000976492.1 YebY family protein -
- 2135882..2136153 - 272 - - Antitoxin
- 2136012..2136115 + 104 - - Toxin
NPL72_RS10320 2136250..2136906 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NPL72_RS10325 2136907..2137098 - 192 WP_001296140.1 YebW family protein -
NPL72_RS10330 2137203..2137439 - 237 WP_001295499.1 YebV family protein -
NPL72_RS10335 2137557..2138996 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T252535 NZ_CP101705:2136012-2136115 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT252535 NZ_CP101705:c2136153-2135882 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References