252522

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3388511..3390030 Replicon chromosome
Accession NZ_CP101704
Organism Xanthomonas oryzae pv. oryzae strain CIX4462

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag NO461_RS15685 Protein ID WP_011259680.1
Coordinates 3388511..3389434 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag NO461_RS15690 Protein ID WP_011409027.1
Coordinates 3389431..3390030 (-) Length 200 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO461_RS15655 (NO461_15660) 3384109..3384261 + 153 Protein_3017 SAM-dependent methyltransferase -
NO461_RS15660 (NO461_15665) 3384373..3385750 + 1378 Protein_3018 IS5 family transposase -
NO461_RS15665 (NO461_15670) 3385770..3386302 + 533 Protein_3019 methyltransferase domain-containing protein -
NO461_RS15670 (NO461_15675) 3386319..3386828 - 510 WP_011259678.1 hypothetical protein -
NO461_RS15675 (NO461_15680) 3387253..3387495 - 243 WP_011259679.1 hypothetical protein -
NO461_RS15680 (NO461_15685) 3387961..3388431 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
NO461_RS15685 (NO461_15690) 3388511..3389434 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
NO461_RS15690 (NO461_15695) 3389431..3390030 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
NO461_RS15695 (NO461_15700) 3390395..3390685 + 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
NO461_RS15700 (NO461_15705) 3390717..3391205 + 489 WP_027703988.1 BrxE family protein -
NO461_RS15705 (NO461_15710) 3391719..3391720 - 2 WP_275685882.1 IS5 family transposase -
NO461_RS15710 (NO461_15715) 3392126..3393159 - 1034 Protein_3028 IS630 family transposase -
NO461_RS15715 (NO461_15720) 3393658..3393948 + 291 WP_256723586.1 hypothetical protein -
NO461_RS15720 (NO461_15725) 3393929..3394303 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T252522 WP_011259680.1 NZ_CP101704:c3389434-3388511 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp


Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT252522 WP_011409027.1 NZ_CP101704:c3390030-3389431 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6


Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References