Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3389567..3391086 Replicon chromosome
Accession NZ_CP101703
Organism Xanthomonas oryzae pv. oryzae strain CIX4506

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag NO458_RS15680 Protein ID WP_011259680.1
Coordinates 3389567..3390490 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag NO458_RS15685 Protein ID WP_011409027.1
Coordinates 3390487..3391086 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO458_RS15645 (NO458_15655) 3384809..3385018 - 210 WP_155296424.1 hypothetical protein -
NO458_RS15650 (NO458_15660) 3385165..3385317 + 153 Protein_3016 SAM-dependent methyltransferase -
NO458_RS15655 (NO458_15665) 3385429..3386806 + 1378 Protein_3017 IS5 family transposase -
NO458_RS15660 (NO458_15670) 3386826..3387358 + 533 Protein_3018 methyltransferase domain-containing protein -
NO458_RS15665 (NO458_15675) 3387375..3387884 - 510 WP_011259678.1 hypothetical protein -
NO458_RS15670 (NO458_15680) 3388309..3388551 - 243 WP_011259679.1 hypothetical protein -
NO458_RS15675 (NO458_15685) 3389017..3389487 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
NO458_RS15680 (NO458_15690) 3389567..3390490 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
NO458_RS15685 (NO458_15695) 3390487..3391086 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
NO458_RS15690 (NO458_15700) 3391451..3391741 + 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
NO458_RS15695 (NO458_15705) 3391773..3392261 + 489 WP_027703988.1 BrxE family protein -
NO458_RS15700 (NO458_15710) 3392775..3392776 - 2 WP_275685882.1 IS5 family transposase -
NO458_RS15705 (NO458_15715) 3393182..3394215 - 1034 Protein_3027 IS630 family transposase -
NO458_RS15710 (NO458_15720) 3394714..3395004 + 291 WP_256723586.1 hypothetical protein -
NO458_RS15715 (NO458_15725) 3394985..3395359 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T252518 WP_011259680.1 NZ_CP101703:c3390490-3389567 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT252518 WP_011409027.1 NZ_CP101703:c3391086-3390487 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References