Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3382710..3384229 Replicon chromosome
Accession NZ_CP101702
Organism Xanthomonas oryzae pv. oryzae strain CIX4509

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag NO460_RS15620 Protein ID WP_011259680.1
Coordinates 3382710..3383633 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag NO460_RS15625 Protein ID WP_011409027.1
Coordinates 3383630..3384229 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO460_RS15590 (NO460_15600) 3378308..3378460 + 153 Protein_3004 SAM-dependent methyltransferase -
NO460_RS15595 (NO460_15605) 3378572..3379949 + 1378 Protein_3005 IS5 family transposase -
NO460_RS15600 (NO460_15610) 3379969..3380501 + 533 Protein_3006 methyltransferase domain-containing protein -
NO460_RS15605 (NO460_15615) 3380518..3381027 - 510 WP_011259678.1 hypothetical protein -
NO460_RS15610 (NO460_15620) 3381452..3381694 - 243 WP_011259679.1 hypothetical protein -
NO460_RS15615 (NO460_15625) 3382160..3382630 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
NO460_RS15620 (NO460_15630) 3382710..3383633 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
NO460_RS15625 (NO460_15635) 3383630..3384229 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
NO460_RS15630 (NO460_15640) 3384594..3384884 + 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
NO460_RS15635 (NO460_15645) 3384916..3385404 + 489 WP_027703988.1 BrxE family protein -
NO460_RS15640 (NO460_15650) 3385918..3385919 - 2 WP_275685882.1 IS5 family transposase -
NO460_RS15645 (NO460_15655) 3386325..3387358 - 1034 Protein_3015 IS630 family transposase -
NO460_RS15650 (NO460_15660) 3387857..3388147 + 291 WP_256723586.1 hypothetical protein -
NO460_RS15655 (NO460_15665) 3388128..3388502 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T252514 WP_011259680.1 NZ_CP101702:c3383633-3382710 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT252514 WP_011409027.1 NZ_CP101702:c3384229-3383630 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References