Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3573416..3574299 Replicon chromosome
Accession NZ_CP101700
Organism Pseudomonas asiatica strain MD9

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NOV18_RS16610 Protein ID WP_239688254.1
Coordinates 3573416..3573802 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F8G488
Locus tag NOV18_RS16615 Protein ID WP_013973163.1
Coordinates 3573850..3574299 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOV18_RS16590 (NOV18_16590) 3568582..3569646 + 1065 WP_015270847.1 TerC family protein -
NOV18_RS16595 (NOV18_16595) 3569786..3571015 - 1230 WP_054572083.1 acyl-CoA dehydrogenase -
NOV18_RS16600 (NOV18_16600) 3571156..3572082 + 927 WP_015270849.1 LysR family transcriptional regulator -
NOV18_RS16605 (NOV18_16605) 3572254..3573408 + 1155 WP_054572084.1 aminotransferase class V-fold PLP-dependent enzyme -
NOV18_RS16610 (NOV18_16610) 3573416..3573802 - 387 WP_239688254.1 RES family NAD+ phosphorylase Toxin
NOV18_RS16615 (NOV18_16615) 3573850..3574299 - 450 WP_013973163.1 DUF2384 domain-containing protein Antitoxin
NOV18_RS16620 (NOV18_16620) 3574398..3575051 - 654 WP_256381797.1 oxygen-insensitive NAD(P)H nitroreductase -
NOV18_RS16625 (NOV18_16625) 3575156..3576079 + 924 WP_054572087.1 LysR family transcriptional regulator -
NOV18_RS16630 (NOV18_16630) 3576127..3576957 + 831 WP_256381798.1 AraC family transcriptional regulator -
NOV18_RS16635 (NOV18_16635) 3577008..3577592 + 585 WP_054572088.1 LysE family translocator -
NOV18_RS16640 (NOV18_16640) 3577732..3578931 - 1200 WP_054572089.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-115)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14242.25 Da        Isoelectric Point: 5.0980

>T252509 WP_239688254.1 NZ_CP101700:c3573802-3573416 [Pseudomonas asiatica]
MRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQPGWSSQTELTRGLGNRF
LDECSALLLPVPSAIMPSTTNYLFNPRHLQANSARLEVEDFTPDSRLF

Download         Length: 387 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17004.59 Da        Isoelectric Point: 6.3405

>AT252509 WP_013973163.1 NZ_CP101700:c3574299-3573850 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F8G488

References