252508

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2317316..2317832 Replicon chromosome
Accession NZ_CP101700
Organism Pseudomonas asiatica strain MD9

Toxin (Protein)


Gene name relE Uniprot ID F8G1E7
Locus tag NOV18_RS11055 Protein ID WP_003259987.1
Coordinates 2317551..2317832 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID F8G1E6
Locus tag NOV18_RS11050 Protein ID WP_013972043.1
Coordinates 2317316..2317561 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOV18_RS11030 (NOV18_11030) 2312728..2313207 - 480 WP_015269934.1 transposase -
NOV18_RS11035 (NOV18_11035) 2313464..2314006 - 543 WP_054572953.1 WYL domain-containing protein -
NOV18_RS11040 (NOV18_11040) 2314742..2315935 + 1194 WP_015269936.1 MFS transporter -
NOV18_RS11045 (NOV18_11045) 2315966..2317072 + 1107 WP_054572951.1 alkene reductase -
NOV18_RS11050 (NOV18_11050) 2317316..2317561 + 246 WP_013972043.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NOV18_RS11055 (NOV18_11055) 2317551..2317832 + 282 WP_003259987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NOV18_RS11060 (NOV18_11060) 2317848..2318480 - 633 WP_015269938.1 BRCT domain-containing protein -
NOV18_RS11065 (NOV18_11065) 2318497..2318892 - 396 WP_023662326.1 hypothetical protein -
NOV18_RS11070 (NOV18_11070) 2318981..2319889 - 909 WP_013972045.1 LysR family transcriptional regulator -
NOV18_RS11075 (NOV18_11075) 2320181..2321485 + 1305 WP_256382094.1 MFS transporter -
NOV18_RS11080 (NOV18_11080) 2321516..2322757 + 1242 WP_015269941.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-76)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10909.78 Da        Isoelectric Point: 10.7594

>T252508 WP_003259987.1 NZ_CP101700:2317551-2317832 [Pseudomonas asiatica]
MTYKLEFLPSALKEWGKLGHTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8779.21 Da        Isoelectric Point: 4.3611

>AT252508 WP_013972043.1 NZ_CP101700:2317316-2317561 [Pseudomonas asiatica]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRLGEKGVPVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F8G1E7

Antitoxin

Source ID Structure
AlphaFold DB F8G1E6

References