Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1718743..1719271 Replicon chromosome
Accession NZ_CP101694
Organism Photobacterium toruni strain WD2103

Toxin (Protein)


Gene name relE Uniprot ID A0A4Q5KBD1
Locus tag NM620_RS08195 Protein ID WP_017020028.1
Coordinates 1718743..1719030 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Q5K8I1
Locus tag NM620_RS08200 Protein ID WP_017020027.1
Coordinates 1719020..1719271 (-) Length 84 a.a.

Genomic Context

NM620_RS08170NM620_RS08175NM620_RS08180NM620_RS08185NM620_RS08190NM620_RS08195NM620_RS08200NM620_RS08205NM620_RS08210NM620_RS08215NM620_RS08220NM620_RS08225NM620_RS08230
Location: 1714077..1714376 (300 bp)
Type: Others
Protein ID: WP_107198478.1
Location: 1714373..1714717 (345 bp)
Type: Others
Protein ID: WP_107295713.1
Location: 1714803..1716329 (1527 bp)
Type: Others
Protein ID: WP_256382864.1
Location: 1716361..1716876 (516 bp)
Type: Others
Protein ID: Protein_1509
Location: 1716873..1717931 (1059 bp)
Type: Others
Protein ID: WP_256382865.1
Location: 1718743..1719030 (288 bp)
Type: Toxin
Protein ID: WP_017020028.1
Location: 1719020..1719271 (252 bp)
Type: Antitoxin
Protein ID: WP_017020027.1
Location: 1719471..1720088 (618 bp)
Type: Others
Protein ID: WP_256382866.1
Location: 1720134..1720226 (93 bp)
Type: Others
Protein ID: WP_005433818.1
Location: 1720241..1721014 (774 bp)
Type: Others
Protein ID: WP_256382867.1
Location: 1721165..1721650 (486 bp)
Type: Others
Protein ID: WP_256382868.1
Location: 1722369..1722857 (489 bp)
Type: Others
Protein ID: WP_256382869.1
Location: 1723590..1724261 (672 bp)
Type: Others
Protein ID: WP_256382870.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NM620_RS081701714077..1714376+300WP_107198478.1hypothetical protein-
NM620_RS081751714373..1714717+345WP_107295713.1IS66 family insertion sequence element accessory protein TnpB-
NM620_RS081801714803..1716329+1527WP_256382864.1IS66 family transposase-
NM620_RS081851716361..1716876+516Protein_1509tyrosine-type recombinase/integrase-
NM620_RS081901716873..1717931+1059WP_256382865.1IS91 family transposase-
NM620_RS081951718743..1719030-288WP_017020028.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NM620_RS082001719020..1719271-252WP_017020027.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
NM620_RS082051719471..1720088-618WP_256382866.1hypothetical protein-
NM620_RS082101720134..1720226-93WP_005433818.1DUF3265 domain-containing protein-
NM620_RS082151720241..1721014-774WP_256382867.1hypothetical protein-
NM620_RS082201721165..1721650-486WP_256382868.1hypothetical protein-
NM620_RS082251722369..1722857-489WP_256382869.1SLATT domain-containing protein-
NM620_RS082301723590..1724261-672WP_256382870.1DUF2726 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1690712..172993439222
-insideIntegron--1718614..17270898475


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-70)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11003.03 Da        Isoelectric Point: 10.4934

>T252507 WP_017020028.1 NZ_CP101694:c1719030-1718743 [Photobacterium toruni]
MTYKLKFLPAAQKEWSKLAPPIKSQFKKKLIERLENPHVPASKLRGYDSVYKIKLRTAGYRLAYEVIDDEIVVYVLAIGK
RDKDAVYKKLASRFG

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9198.41 Da        Isoelectric Point: 4.0174

>AT252507 WP_017020027.1 NZ_CP101694:c1719271-1719020 [Photobacterium toruni]
MRQVLADCSASISELKKNPTALLNEADGSAIAILNHNKPAAYLVPAETYEFLMDMLDDYELSKLVESRRLDLSDAVEVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4Q5KBD1

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4Q5K8I1

References