Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6271138..6272797 Replicon chromosome
Accession NC_015563
Organism Delftia sp. Cs1-4

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag DELCS14_RS27555 Protein ID WP_172642972.1
Coordinates 6271967..6272797 (-) Length 277 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID F6ALN8
Locus tag DELCS14_RS27550 Protein ID WP_012202883.1
Coordinates 6271138..6271944 (-) Length 269 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DELCS14_RS27525 6266631..6267401 - 771 WP_012202888.1 SDR family oxidoreductase -
DELCS14_RS30260 6268209..6268484 + 276 WP_013804510.1 hypothetical protein -
DELCS14_RS27530 6268748..6269095 + 348 WP_013804511.1 type II toxin-antitoxin system RelE/ParE family toxin -
DELCS14_RS27535 6269092..6269400 + 309 WP_013804512.1 XRE family transcriptional regulator -
DELCS14_RS27540 6269413..6270174 - 762 WP_013804513.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
DELCS14_RS27545 6270286..6271083 - 798 WP_013804514.1 aspartate dehydrogenase -
DELCS14_RS27550 6271138..6271944 - 807 WP_012202883.1 IclR family transcriptional regulator Antitoxin
DELCS14_RS27555 6271967..6272797 - 831 WP_172642972.1 alpha/beta fold hydrolase Toxin
DELCS14_RS27560 6272971..6273501 - 531 WP_012202881.1 cupin domain-containing protein -
DELCS14_RS27565 6273702..6274898 - 1197 WP_013804516.1 MFS transporter -
DELCS14_RS27570 6274921..6275805 - 885 WP_013804517.1 NAD(P)-dependent oxidoreductase -
DELCS14_RS27575 6275942..6276532 - 591 WP_013804518.1 TetR/AcrR family transcriptional regulator -
DELCS14_RS27580 6276614..6277105 - 492 WP_013804519.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(35-262)

Antitoxin

Transcription regulator IclR, C-terminal

(137-255)


Sequences

Toxin        


Download         Length: 277 a.a.        Molecular weight: 28671.79 Da        Isoelectric Point: 6.7487

>T25244 WP_172642972.1 NC_015563:c6272797-6271967 [Delftia sp. Cs1-4]
MEQRLQAQFPEHLIALPGGAQAAWREAGDTASDFAVVMLHGISSGAASWLDVALALAPRTRVLAWDAPGYGRSTPLAPDA
PTGADYARVLEQSLQALGVRRCLLVGHSLGALMGTPWAVQAGAGRVQQLVLISPAGGYGAPGMGEQQAKVRQGRLAALQE
KGIEGLAAAIDQRLVSPAAPEPVRQWVRWNTARLHAAGYAQAVELLCGSDLGQAAGQLAMPVEVWVGEHDVVTPPAACAA
WAARLGARYVTLAAAGHASVVEQPADVAQRLATLLT

Download         Length: 831 bp

>T25244 NC_015563:c6272797-6271967 [Delftia sp. Cs1-4]
ATGGAGCAGCGCCTTCAGGCGCAGTTCCCCGAACATCTCATCGCCCTGCCCGGTGGCGCTCAGGCCGCCTGGCGCGAGGC
CGGCGACACGGCCTCGGACTTTGCCGTGGTGATGCTGCACGGCATCAGCTCGGGCGCCGCCTCCTGGCTGGACGTGGCCC
TGGCGCTGGCGCCGCGCACGCGTGTGCTGGCCTGGGACGCGCCCGGCTATGGCCGCTCCACGCCGCTGGCACCCGACGCG
CCCACGGGCGCCGACTACGCCCGCGTGCTGGAGCAGTCGCTGCAGGCGCTGGGCGTGCGCCGCTGCCTGCTGGTGGGCCA
CTCGCTGGGTGCGCTCATGGGCACGCCCTGGGCGGTGCAGGCCGGTGCCGGGCGCGTGCAGCAACTGGTGCTGATCAGCC
CCGCTGGCGGCTATGGCGCACCCGGCATGGGCGAGCAGCAGGCCAAGGTACGCCAGGGCCGTCTTGCGGCCCTTCAGGAA
AAAGGCATCGAAGGCCTGGCCGCCGCCATCGACCAGCGCCTGGTCTCGCCCGCCGCACCCGAGCCCGTGCGCCAATGGGT
GCGCTGGAACACGGCGCGCCTGCATGCTGCCGGCTACGCCCAGGCCGTGGAGCTGCTGTGCGGCAGCGACCTGGGGCAGG
CGGCCGGGCAACTGGCCATGCCGGTCGAGGTCTGGGTGGGCGAGCACGACGTGGTCACGCCGCCCGCTGCCTGCGCGGCC
TGGGCCGCAAGGCTGGGCGCCCGGTACGTTACGCTTGCGGCAGCCGGCCATGCCTCTGTCGTCGAACAACCTGCGGATGT
CGCACAGAGGCTGGCCACCCTGCTGACCTGA

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29330.45 Da        Isoelectric Point: 5.7085

>AT25244 WP_012202883.1 NC_015563:c6271944-6271138 [Delftia sp. Cs1-4]
MSDTSETLSNDNDRYTVPALERGLRLLACFTPSQPVWSAPDLARTLALPRSTVFRMLTTLENMGYLQRSGTEYRLGLSVL
RLGYDYLSTQPLAQLAEPVLQALCERLGFTTNLALLDGTSVVYVARIAPAGAFQGAVRVGSRLPAHATVLGRALLQDMDA
DQLRELFGGSELPQFSESTPRDVQQLQQLLLQDRERGYAMGEGFYEPGVSSIAAPVRDAQGRIIAGLGMAVAFTEIAPGR
MAHWVEQVREAAVELTGHLRTQHPGFLR

Download         Length: 807 bp

>AT25244 NC_015563:c6271944-6271138 [Delftia sp. Cs1-4]
ATGAGCGACACCTCCGAAACCCTCTCGAACGACAACGACCGCTACACCGTCCCCGCGCTGGAGCGCGGCCTGCGCCTGCT
GGCCTGCTTCACGCCTTCGCAGCCCGTGTGGAGCGCGCCCGACCTGGCGCGCACCCTGGCGCTGCCGCGTTCCACGGTGT
TCCGGATGCTGACGACGCTGGAGAACATGGGGTATCTGCAACGCTCGGGCACCGAGTACCGGCTGGGCCTGTCCGTGCTG
CGCCTGGGCTACGACTACCTGTCCACCCAGCCGCTGGCCCAACTGGCCGAGCCCGTGCTGCAGGCGCTGTGCGAGCGCCT
GGGCTTCACCACCAACCTGGCGCTGCTGGACGGCACCTCCGTGGTCTACGTGGCGCGCATCGCGCCGGCCGGCGCCTTCC
AGGGCGCCGTGCGCGTGGGCTCGCGCCTGCCCGCCCATGCCACCGTGCTGGGCCGCGCCCTGTTGCAGGACATGGACGCA
GACCAGCTGCGAGAACTCTTCGGCGGCAGCGAACTGCCGCAATTCTCGGAAAGCACGCCGCGTGACGTGCAGCAACTGCA
GCAACTGCTGCTGCAGGACCGCGAGCGCGGCTACGCCATGGGCGAGGGCTTCTACGAGCCCGGCGTCTCCAGCATTGCCG
CGCCCGTGCGCGATGCGCAGGGCCGCATCATCGCGGGCCTGGGCATGGCCGTGGCATTTACCGAAATCGCACCCGGGCGC
ATGGCGCACTGGGTGGAACAGGTGCGCGAGGCCGCCGTCGAGCTGACGGGCCACCTGCGCACCCAGCATCCTGGTTTTCT
GCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A031HDN8

References