Detailed information of TA system TA025242

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RelE(toxin)
• Location: 5745468..5746033
• Replicon: chromosome
• Accession: NC_015563
• Organism: Delftia sp. Cs1-4

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: DELCS14_RS25215
• Protein ID: WP_043796449.1
• Coordinates: 5745468..5745752 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: F6AVI5
• Locus tag: DELCS14_RS25220
• Protein ID: WP_013804138.1
• Coordinates: 5745749..5746033 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DELCS14_RS25200	5742128..5742697	+	570	WP_013804134.1	VUT family protein	-
DELCS14_RS25205	5742863..5744239	-	1377	WP_013804135.1	amidohydrolase	-
DELCS14_RS25210	5744336..5745382	+	1047	WP_013804136.1	helix-turn-helix domain-containing protein	-
DELCS14_RS25215	5745468..5745752	-	285	WP_043796449.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DELCS14_RS25220	5745749..5746033	-	285	WP_013804138.1	hypothetical protein	Antitoxin
DELCS14_RS25225	5746195..5747193	-	999	WP_013804139.1	tripartite tricarboxylate transporter substrate binding protein	-
DELCS14_RS25230	5747348..5748277	-	930	WP_013804140.1	glyoxylate/hydroxypyruvate reductase A	-
DELCS14_RS25235	5748286..5749056	-	771	WP_012203336.1	class II aldolase/adducin family protein	-
DELCS14_RS25240	5749104..5750648	-	1545	WP_013804141.1	acyl--CoA ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10630.28 Da
• Isoelectric Point: 10.2316

>T25242 WP_043796449.1 NC_015563:c5745752-5745468 [Delftia sp. Cs1-4]
VKLVWTRPAAADRREIRAYIAQDNPSAALALDERFSEIAGHLIDHPLLGRVGRVAGTRELVVHPNYILVYDMIADSVRVL
RVLHAARQWPPQRT

Nucleotide

• Length: 285 bp

>T25242 NC_015563:c5745752-5745468 [Delftia sp. Cs1-4]
GTGAAGCTGGTATGGACACGTCCAGCAGCCGCCGACAGGCGGGAGATCCGTGCCTACATCGCTCAAGACAATCCGTCCGC
CGCGCTGGCCCTTGACGAGCGGTTTTCCGAAATAGCGGGGCATTTGATCGACCATCCCCTGCTTGGCCGAGTCGGGCGCG
TCGCCGGCACGCGCGAACTGGTGGTGCATCCCAACTACATCCTGGTCTATGACATGATCGCCGACAGCGTGCGTGTGCTG
CGCGTCCTGCATGCGGCCCGCCAGTGGCCGCCGCAGCGGACATAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10488.71 Da
• Isoelectric Point: 4.8358

>AT25242 WP_013804138.1 NC_015563:c5746033-5745749 [Delftia sp. Cs1-4]
MSEATFTFRVDEVLKNDFATAAKACDRTGAQLLRDFMRSYVQQQEQTAAHDAWLRAQVQVGIDAANAGEVLSADEVEAEA
RAWRAEMRRKISAP

Nucleotide

• Length: 285 bp

>AT25242 NC_015563:c5746033-5745749 [Delftia sp. Cs1-4]
ATGAGCGAAGCAACTTTCACCTTCCGGGTCGATGAGGTCCTGAAAAACGACTTTGCCACCGCCGCCAAAGCCTGCGACCG
CACGGGTGCGCAGTTGCTGCGCGACTTCATGCGCTCATATGTGCAACAGCAGGAACAGACTGCGGCACATGACGCATGGT
TGCGCGCGCAAGTGCAGGTCGGCATCGACGCGGCCAACGCGGGCGAGGTGCTGTCTGCCGATGAAGTGGAGGCAGAAGCA
CGGGCATGGCGGGCCGAAATGCGCAGGAAGATTTCCGCGCCGTGA

Structures

Antitoxin

• AlphaFold DB: A0A072T6Z7