Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 4351403..4352986 Replicon chromosome
Accession NZ_CP101622
Organism Stenotrophomonas maltophilia strain CYZ

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag DWB40_RS20095 Protein ID WP_038646246.1
Coordinates 4351664..4352986 (+) Length 441 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag DWB40_RS20090 Protein ID WP_005407534.1
Coordinates 4351403..4351660 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWB40_RS20080 4346748..4347383 - 636 WP_005407536.1 hypothetical protein -
DWB40_RS20085 4347555..4351241 + 3687 WP_062606399.1 indolepyruvate ferredoxin oxidoreductase family protein -
DWB40_RS20090 4351403..4351660 + 258 WP_005407534.1 helix-turn-helix transcriptional regulator Antitoxin
DWB40_RS20095 4351664..4352986 + 1323 WP_038646246.1 type II toxin-antitoxin system HipA family toxin Toxin
DWB40_RS20100 4352987..4353601 - 615 WP_062606401.1 DUF938 domain-containing protein -
DWB40_RS20105 4354291..4355922 + 1632 WP_062606899.1 TldD/PmbA family protein -
DWB40_RS20110 4355953..4357587 + 1635 WP_005407530.1 TldD/PmbA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-70)


Sequences

Toxin        


Download         Length: 441 a.a.        Molecular weight: 49039.94 Da        Isoelectric Point: 6.9606

>T252408 WP_038646246.1 NZ_CP101622:4351664-4352986 [Stenotrophomonas maltophilia]
MGTLQVWMNGVEVALWDDVRNGSSRLSYVSQWISSPQSRPLSLSLPLLPDGESHRGNVVNDYFDNLLPDNVAIRNRIRDR
FATRGSDTFDLLEAIGRDCVGAVQLLPPAHPPEDIQQITCEVLDEAGVATILRQVTTGNLPGAPSRDDAFRISIAGAQEK
TGLLLHAGKWCIPTGNTPSTHIFKLPLGIVGNMRADMHQSVENEWLCMHLLSAFDIPVAETQMGRFNDQRALIVERFDRR
LSADRRWWLRLPQEDMCQVFGLPAARKYESDGGPGIVPIMDLLRQSEHPEDRAIFFKTQILFWMLAATDGHAKNFSVHLE
AGGRFRLTPVYDVLSVYPILGRGPNQLDPRNAQLAMAVHGKNRHRKLHLVRRRHWNETARACGVADGAEPWIKTLIAAVE
PAIQQVTRQLPDDFPSNVSEPIFNGLRAAAARLSSMAPEA

Download         Length: 1323 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9584.97 Da        Isoelectric Point: 11.8468

>AT252408 WP_005407534.1 NZ_CP101622:4351403-4351660 [Stenotrophomonas maltophilia]
MDRPLHTVRTAQQLAPLMRAFRRQAGLSQAQLAERLGISRQAVGALERDPASASFERLMRIWAVLGLEVSLQQRSPQENT
SSLEW

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References