Detailed information of TA system TA025238

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3662654..3663326
• Replicon: chromosome
• Accession: NC_015559
• Organism: Marinomonas posidonica IVIA-Po-181

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MAR181_RS16880
• Protein ID: WP_013797813.1
• Coordinates: 3662952..3663326 (-)
• Length: 125 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MAR181_RS16875
• Protein ID: WP_013797812.1
• Coordinates: 3662654..3662959 (-)
• Length: 102 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MAR181_RS16860	3658413..3660206	+	1794	WP_144011345.1	allophanate hydrolase	-
MAR181_RS16865	3660309..3661427	-	1119	WP_013797810.1	FAD-dependent monooxygenase	-
MAR181_RS16870	3661539..3662426	+	888	WP_013797811.1	LysR family transcriptional regulator	-
MAR181_RS16875	3662654..3662959	-	306	WP_013797812.1	DNA-binding transcriptional regulator	Antitoxin
MAR181_RS16880	3662952..3663326	-	375	WP_013797813.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MAR181_RS16885	3663498..3664436	+	939	WP_013797814.1	hypothetical protein	-
MAR181_RS16890	3664638..3665357	-	720	WP_013797815.1	single-stranded DNA-binding protein	-
MAR181_RS16895	3665388..3666746	-	1359	WP_013797816.1	MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (1-120)

Antitoxin

• Cro/C1-type helix-turn-helix domain (43-89)

Sequences

Toxin

Protein

• Length: 125 a.a.
• Molecular weight: 13823.98 Da
• Isoelectric Point: 10.2474

>T25238 WP_013797813.1 NC_015559:c3663326-3662952 [Marinomonas posidonica IVIA-Po-181]
MRIFKNKAFHRWAIKEGLADSALITAVDEIEKGLVDADLGGHVFKKRVALGGRGKSAGARTLLAYRFGQRAFFMYGFAKN
SRANIDADELRALRRLAKELLEYSDIELIIAIEHGAFIEVKNNG

Nucleotide

• Length: 375 bp

>T25238 NC_015559:c3663326-3662952 [Marinomonas posidonica IVIA-Po-181]
ATGCGGATATTTAAAAATAAGGCATTCCATCGCTGGGCGATTAAGGAAGGTTTGGCTGATAGTGCTTTGATAACAGCCGT
TGATGAAATTGAAAAAGGCTTAGTGGACGCGGATTTAGGTGGTCATGTGTTCAAAAAACGCGTGGCACTCGGTGGTCGAG
GAAAAAGCGCTGGTGCCAGAACACTGTTAGCTTACAGATTTGGCCAAAGAGCATTCTTCATGTATGGCTTTGCTAAAAAC
AGTCGAGCAAATATTGATGCTGATGAATTGAGAGCGCTAAGAAGGTTAGCGAAAGAATTGCTTGAGTACAGTGATATTGA
GCTCATTATCGCCATTGAACACGGTGCATTTATCGAGGTAAAAAATAATGGATAA

Antitoxin

Protein

• Length: 102 a.a.
• Molecular weight: 11202.03 Da
• Isoelectric Point: 9.5768

>AT25238 WP_013797812.1 NC_015559:c3662959-3662654 [Marinomonas posidonica IVIA-Po-181]
MDKSILDMVQDTAQQLYDAGVMKETTLREFDAMCLPPVKVFTAEQIKSIRTKNRASQGVFAAYLNTSKSTVQKWEQGVKK
PNGPSLKLLNLVADKGLDVLV

Nucleotide

• Length: 306 bp

>AT25238 NC_015559:c3662959-3662654 [Marinomonas posidonica IVIA-Po-181]
ATGGATAAATCAATCTTAGACATGGTGCAAGATACCGCTCAGCAGTTGTACGATGCTGGCGTGATGAAAGAGACGACTCT
GCGTGAGTTTGATGCCATGTGTTTGCCTCCAGTAAAAGTGTTCACAGCCGAGCAAATTAAAAGTATCCGTACAAAAAATC
GAGCGAGTCAGGGCGTCTTTGCTGCTTATTTGAATACTAGCAAGTCCACAGTGCAAAAGTGGGAGCAAGGCGTTAAGAAG
CCGAATGGGCCGTCATTAAAACTGTTGAATTTGGTCGCCGACAAAGGTCTGGATGTGCTTGTATAG