Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 873993..874653 Replicon chromosome
Accession NZ_CP101613
Organism Erwinia persicina strain SR15

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NOG67_RS04015 Protein ID WP_255851444.1
Coordinates 874240..874653 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A354DN60
Locus tag NOG67_RS04010 Protein ID WP_062744288.1
Coordinates 873993..874259 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOG67_RS03990 (NOG67_03980) 870445..871188 + 744 WP_118663257.1 SDR family oxidoreductase -
NOG67_RS03995 (NOG67_03985) 871293..871901 - 609 WP_062744290.1 HD domain-containing protein -
NOG67_RS04000 (NOG67_03990) 872111..872764 + 654 WP_062744348.1 hemolysin III family protein -
NOG67_RS04005 (NOG67_03995) 872780..873766 - 987 WP_255851443.1 tRNA-modifying protein YgfZ -
NOG67_RS04010 (NOG67_04000) 873993..874259 + 267 WP_062744288.1 FAD assembly factor SdhE Antitoxin
NOG67_RS04015 (NOG67_04005) 874240..874653 + 414 WP_255851444.1 protein YgfX Toxin
NOG67_RS04020 (NOG67_04010) 874646..875341 + 696 WP_062744286.1 two-component system response regulator CreB -
NOG67_RS04025 (NOG67_04015) 875341..876765 + 1425 WP_255851445.1 two-component system sensor histidine kinase CreC -
NOG67_RS04030 (NOG67_04020) 876848..878209 + 1362 WP_137269030.1 cell envelope integrity protein CreD -
NOG67_RS04035 (NOG67_04025) 878307..878825 - 519 WP_255851446.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16136.90 Da        Isoelectric Point: 11.8432

>T252377 WP_255851444.1 NZ_CP101613:874240-874653 [Erwinia persicina]
VVRCHCNLRLSRHAQSSSLLLHGGVMLLLLLAPWPPEASLVKVALLLLTGGECLRSCRRTRRWQGLFVLLSGRRVQWHQA
QWQMVSPPWMTRHAVRLSLRDNQGRHERLWLFADGMDNSEWRLLRQQLLSKKEWRDE

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10580.97 Da        Isoelectric Point: 4.5392

>AT252377 WP_062744288.1 NZ_CP101613:873993-874259 [Erwinia persicina]
MDISNKSRIHWACRRGMRELDISIMPFFEYEYDSLNDQDKQLFVRLLENDDPDLFNWLMNHGEPADDELKRMVALIQDRN
RERGPVPL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A354DN60

References