Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3378736..3380139 Replicon chromosome
Accession NC_015556
Organism Pseudomonas fulva 12-X

Toxin (Protein)


Gene name - Uniprot ID F6A9B9
Locus tag PSEFU_RS15810 Protein ID WP_013792247.1
Coordinates 3379570..3380139 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID F6A9B8
Locus tag PSEFU_RS15805 Protein ID WP_013792246.1
Coordinates 3378736..3379566 (-) Length 277 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSEFU_RS15785 3374529..3376595 - 2067 WP_013792242.1 pyridoxamine 5'-phosphate oxidase family protein -
PSEFU_RS15790 3376628..3377245 - 618 WP_013792243.1 glutathione S-transferase -
PSEFU_RS15795 3377380..3377709 - 330 WP_013792244.1 AzlD domain-containing protein -
PSEFU_RS15800 3377709..3378419 - 711 WP_013792245.1 AzlC family ABC transporter permease -
PSEFU_RS15805 3378736..3379566 - 831 WP_013792246.1 AraC family transcriptional regulator Antitoxin
PSEFU_RS15810 3379570..3380139 - 570 WP_013792247.1 GNAT family N-acetyltransferase Toxin
PSEFU_RS15815 3380355..3383831 + 3477 WP_013792248.1 hybrid sensor histidine kinase/response regulator -
PSEFU_RS15820 3383965..3384303 + 339 WP_013792249.1 FKBP-type peptidyl-prolyl cis-trans isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(15-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21627.96 Da        Isoelectric Point: 8.4935

>T25237 WP_013792247.1 NC_015556:c3380139-3379570 [Pseudomonas fulva 12-X]
MFKPQLITLQRGALRIEPLLDGDIPALVSLAEANRDELLYMSGTQRLDWYRLALQEQREERALPFVIRLADQIVGTTRFA
DFMPTLPAVEIGWTWLDAAQHGTGLNNMIKYLMLRHAFESWQMVRVQLKTAASNQRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDQEWPVVKAGLEARFGV

Download         Length: 570 bp

>T25237 NC_015556:c3380139-3379570 [Pseudomonas fulva 12-X]
ATGTTCAAGCCGCAATTGATCACCCTGCAGCGCGGTGCCCTGCGCATCGAACCGTTGCTCGATGGCGATATTCCGGCGCT
GGTCAGCCTGGCCGAAGCCAATCGCGATGAGCTGCTCTACATGAGCGGCACCCAGCGCCTGGACTGGTACCGCCTGGCCC
TGCAGGAGCAGCGCGAAGAGCGCGCCTTGCCCTTCGTGATTCGCCTCGCCGACCAGATCGTCGGCACCACGCGCTTCGCC
GACTTCATGCCGACCCTGCCGGCGGTGGAAATCGGCTGGACCTGGCTGGACGCCGCCCAGCACGGCACCGGCCTGAACAA
CATGATCAAGTACCTGATGCTGCGCCACGCCTTCGAGAGCTGGCAGATGGTTCGCGTGCAACTGAAAACCGCCGCCAGCA
ACCAGCGCTCCCAGCGCGCCATCGAAAAGCTCGGCGCGGTTCGCGAGGGCCTGCTGCGCAATCATCGCCGCCTGGCCGAC
GGGCGCCTCGACGACACCGTGCTGTACAGCATCACCGATCAGGAATGGCCGGTGGTCAAGGCCGGGCTGGAGGCACGCTT
CGGCGTGTGA

Antitoxin


Download         Length: 277 a.a.        Molecular weight: 30757.17 Da        Isoelectric Point: 10.0515

>AT25237 WP_013792246.1 NC_015556:c3379566-3378736 [Pseudomonas fulva 12-X]
MPTGERIRFWESPALAGVELLQARYIKQRFTPHVHEGFVFTVIEHGAQRFRHRGADHLAPVGSMVLINPDEVHTGSSAHE
QGWLYRAFYPAPAQVNGVLDELGLAHRGLPSFAASVLQDVELHRAFGQLHRLLDSDAGVLHQQTAWRETLLMLFQRHAGV
RQAAAAGLEPRAVSLAKELLAARLGEPPSLEELATAVNLSPFHFARVFRRATGLPPHAWLQQRRLEQARALLRDGCAPLS
VALQLGFADQSHLTRQFKQVYGVGPGEYRKACHRRP

Download         Length: 831 bp

>AT25237 NC_015556:c3379566-3378736 [Pseudomonas fulva 12-X]
ATGCCCACCGGCGAGCGCATCCGCTTCTGGGAAAGCCCCGCCCTGGCCGGCGTGGAGCTGCTGCAGGCGCGCTACATCAA
GCAACGCTTCACCCCGCACGTACACGAAGGTTTCGTGTTCACCGTGATCGAGCATGGCGCCCAGCGCTTTCGCCACCGTG
GCGCGGATCACCTGGCGCCGGTCGGCAGCATGGTGCTGATCAATCCGGACGAGGTGCACACCGGCTCGTCGGCCCACGAG
CAGGGTTGGTTGTACCGCGCCTTCTACCCGGCGCCGGCCCAGGTCAATGGCGTGCTCGACGAACTGGGCCTGGCGCACCG
CGGCCTGCCGTCGTTCGCCGCCAGCGTGCTGCAGGACGTCGAACTGCATCGGGCCTTCGGCCAGTTGCACCGCCTGCTCG
ACAGTGACGCCGGCGTGCTGCACCAGCAGACGGCATGGCGCGAGACATTGCTGATGCTGTTCCAGCGTCATGCCGGGGTC
AGGCAGGCGGCTGCCGCCGGTCTGGAGCCGCGGGCGGTGAGCCTGGCCAAGGAGCTGCTGGCCGCGCGCCTGGGCGAGCC
GCCATCGCTGGAAGAACTGGCCACCGCGGTGAACCTCTCGCCGTTCCATTTCGCCCGGGTGTTTCGCCGCGCCACCGGCC
TGCCGCCCCACGCCTGGTTGCAGCAACGCCGGTTGGAGCAGGCGCGGGCGCTGCTGCGTGACGGCTGTGCGCCGCTGAGC
GTGGCGCTGCAACTGGGCTTCGCCGACCAAAGCCACCTGACGCGACAGTTCAAGCAGGTGTATGGCGTGGGGCCCGGTGA
ATACCGCAAGGCTTGCCATCGCCGCCCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F6A9B9

Antitoxin

Source ID Structure
AlphaFold DB F6A9B8

References