Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4283462..4284011 Replicon chromosome
Accession NZ_CP101595
Organism Cronobacter dublinensis strain CFSA A84

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NNQ27_RS20675 Protein ID WP_105650996.1
Coordinates 4283462..4283770 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NNQ27_RS20680 Protein ID WP_199782776.1
Coordinates 4283772..4284011 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNQ27_RS20655 (NNQ27_20655) 4278700..4279458 - 759 WP_275885317.1 SDR family oxidoreductase -
NNQ27_RS20660 (NNQ27_20660) 4279577..4280476 + 900 WP_275885318.1 LysR family transcriptional regulator -
NNQ27_RS20665 (NNQ27_20665) 4280529..4281563 + 1035 WP_038874348.1 inner membrane protein YhjD -
NNQ27_RS20670 (NNQ27_20670) 4281838..4283166 + 1329 WP_275885319.1 MFS transporter -
NNQ27_RS20675 (NNQ27_20675) 4283462..4283770 - 309 WP_105650996.1 CcdB family protein Toxin
NNQ27_RS20680 (NNQ27_20680) 4283772..4284011 - 240 WP_199782776.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NNQ27_RS20685 (NNQ27_20685) 4284129..4286186 - 2058 WP_275885320.1 AsmA family protein -
NNQ27_RS20690 (NNQ27_20690) 4286251..4287024 - 774 WP_007753642.1 cyclic-guanylate-specific phosphodiesterase -
NNQ27_RS20695 (NNQ27_20695) 4287257..4288189 + 933 WP_275885321.1 sugar kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11716.61 Da        Isoelectric Point: 6.2118

>T252369 WP_105650996.1 NZ_CP101595:c4283770-4283462 [Cronobacter dublinensis]
MQYQIYRNTSTNKKYPYLIDVQSDLIDVLTTRVVIPLVPRFMAQKPLPERMCPVVEVDGDEYIVMTHEMASVGKSVLGEH
AASALPWRQHIKNAIDFMFDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9274.46 Da        Isoelectric Point: 5.7303

>AT252369 WP_199782776.1 NZ_CP101595:c4284011-4283772 [Cronobacter dublinensis]
MNVVEKPPKRTVSVTIDEALYQRARAQGINLSQRLSLVLEEDLRAIERQQWKDENREGLLELNRIADECGHFADEHRKF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References