Detailed information of TA system TA025236

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 810365..810834
• Replicon: chromosome
• Accession: NC_015556
• Organism: Pseudomonas fulva 12-X

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PSEFU_RS03740
• Protein ID: WP_013789853.1
• Coordinates: 810559..810834 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: F6AK74
• Locus tag: PSEFU_RS03735
• Protein ID: WP_013789852.1
• Coordinates: 810365..810559 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSEFU_RS03715	805568..806518	+	951	WP_013789848.1	bifunctional riboflavin kinase/FAD synthetase	-
PSEFU_RS03720	806515..809349	+	2835	WP_013789849.1	isoleucine--tRNA ligase	-
PSEFU_RS03725	809380..809886	+	507	WP_013789850.1	signal peptidase II	-
PSEFU_RS03730	809879..810325	+	447	WP_013789851.1	FKBP-type peptidyl-prolyl cis-trans isomerase	-
PSEFU_RS03735	810365..810559	+	195	WP_013789852.1	hypothetical protein	Antitoxin
PSEFU_RS03740	810559..810834	+	276	WP_013789853.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PSEFU_RS03745	810870..811814	+	945	WP_013789854.1	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	-
PSEFU_RS03750	811964..812710	+	747	WP_013789855.1	dienelactone hydrolase family protein	-
PSEFU_RS03755	812893..813420	-	528	WP_013789856.1	inorganic diphosphatase	-
PSEFU_RS03760	813459..814328	-	870	WP_013789857.1	zinc-dependent peptidase	-
PSEFU_RS03765	814395..814850	-	456	WP_013789858.1	GNAT family N-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10561.29 Da
• Isoelectric Point: 9.3682

>T25236 WP_013789853.1 NC_015556:810559-810834 [Pseudomonas fulva 12-X]
MLPIVWRATARDDLLQIIRYIANEDPKAARQLKERLESVVLPLAEHPYLYRFGRVPGTRELIAHPNYILVYRVAADAVEV
VNVLHARQQYP

Nucleotide

• Length: 276 bp

>T25236 NC_015556:810559-810834 [Pseudomonas fulva 12-X]
ATGCTGCCGATCGTCTGGCGTGCCACTGCCAGGGACGATCTTTTGCAGATCATTCGTTACATCGCCAATGAAGACCCCAA
GGCTGCCAGGCAGCTAAAAGAGCGATTGGAGTCGGTTGTGCTGCCGTTGGCTGAGCATCCCTATCTGTATCGTTTTGGTC
GGGTGCCCGGAACACGCGAGCTGATCGCTCATCCAAACTACATTCTGGTTTACCGAGTAGCCGCTGACGCTGTGGAAGTG
GTGAACGTTCTTCATGCTCGCCAACAGTATCCTTGA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7201.94 Da
• Isoelectric Point: 5.6726

>AT25236 WP_013789852.1 NC_015556:810365-810559 [Pseudomonas fulva 12-X]
MSVQRSPIVSEFETQESADSHDGWFRRKVAESLADSRGVVAHDQVMADVEAVISEAEARRRSKR

Nucleotide

• Length: 195 bp

>AT25236 NC_015556:810365-810559 [Pseudomonas fulva 12-X]
ATGAGCGTACAGCGTTCCCCCATCGTGTCGGAGTTCGAGACCCAGGAATCGGCGGACAGCCACGACGGCTGGTTTCGCCG
CAAGGTCGCGGAATCTCTCGCAGACTCTCGAGGTGTGGTTGCCCATGATCAGGTGATGGCCGATGTCGAGGCCGTCATCA
GCGAGGCAGAGGCACGGCGGCGGAGTAAGCGTTGA

Structures

Antitoxin

• AlphaFold DB: F6AK74