Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 223913..224718 Replicon chromosome
Accession NZ_CP101595
Organism Cronobacter dublinensis strain CFSA A84

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag NNQ27_RS01275 Protein ID WP_275885523.1
Coordinates 224191..224718 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NNQ27_RS01270 Protein ID WP_275886341.1
Coordinates 223913..224194 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNQ27_RS01255 (NNQ27_01275) 219843..221048 - 1206 WP_275885522.1 FMN-dependent L-lactate dehydrogenase LldD -
NNQ27_RS01260 (NNQ27_01280) 221048..221833 - 786 WP_038875512.1 transcriptional regulator LldR -
NNQ27_RS01265 (NNQ27_01285) 221830..223485 - 1656 WP_105685872.1 L-lactate permease -
NNQ27_RS01270 (NNQ27_01290) 223913..224194 + 282 WP_275886341.1 DUF1778 domain-containing protein Antitoxin
NNQ27_RS01275 (NNQ27_01295) 224191..224718 + 528 WP_275885523.1 GNAT family N-acetyltransferase Toxin
NNQ27_RS01280 (NNQ27_01300) 224758..225120 - 363 WP_007729196.1 YibL family ribosome-associated protein -
NNQ27_RS01285 (NNQ27_01305) 225251..226765 - 1515 WP_032967552.1 glycerol kinase GlpK -
NNQ27_RS01290 (NNQ27_01310) 226787..227635 - 849 WP_007729203.1 MIP/aquaporin family protein -
NNQ27_RS01295 (NNQ27_01315) 228070..228309 + 240 WP_275885524.1 septal ring assembly protein ZapB -
NNQ27_RS01300 (NNQ27_01320) 228359..228844 - 486 WP_007729210.1 ribonuclease E activity regulator RraA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-148)

Antitoxin

Vibrio phage ICP1, Orf50

(9-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19520.26 Da        Isoelectric Point: 8.6549

>T252359 WP_275885523.1 NZ_CP101595:224191-224718 [Cronobacter dublinensis]
MTLKRGVFSYAPEHGWKTASFDCGCDTLNDFLRQRLAVQQQRNVLRAYVVLTNEPEPAVAGYYTLSGASFERSLFGERKR
QIPYDSAPCVLLGRLAVDKTHAGKGIGSMLVADAARRVYDVARAVGVYAMFVEAKDAHAAQFYQQLGFLQAESTDERQRL
FFPIRALDALFTTTP

Download         Length: 528 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10480.85 Da        Isoelectric Point: 6.7205

>AT252359 WP_275886341.1 NZ_CP101595:223913-224194 [Cronobacter dublinensis]
MPAPSKKDRLECRLSTEDKAAIEAAASLSNTSVSQFIVDAARARARVLLEEHHRIRLTEQGWHAVMAALDNPPAPNEKLK
RAFERLDNGEFWE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References