Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4210413..4210962 Replicon chromosome
Accession NZ_CP101591
Organism Cronobacter dublinensis strain CFSA A14

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NMY27_RS20240 Protein ID WP_105630385.1
Coordinates 4210413..4210721 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NMY27_RS20245 Protein ID WP_199782193.1
Coordinates 4210723..4210962 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMY27_RS20220 (NMY27_20200) 4205646..4206404 - 759 WP_275876202.1 SDR family oxidoreductase -
NMY27_RS20225 (NMY27_20205) 4206523..4207422 + 900 WP_275876203.1 LysR family transcriptional regulator -
NMY27_RS20230 (NMY27_20210) 4207475..4208509 + 1035 WP_007753639.1 inner membrane protein YhjD -
NMY27_RS20235 (NMY27_20215) 4208784..4210112 + 1329 WP_007753640.1 MFS transporter -
NMY27_RS20240 (NMY27_20220) 4210413..4210721 - 309 WP_105630385.1 CcdB family protein Toxin
NMY27_RS20245 (NMY27_20225) 4210723..4210962 - 240 WP_199782193.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NMY27_RS20250 (NMY27_20230) 4211080..4213137 - 2058 WP_275876204.1 AsmA family protein -
NMY27_RS20255 (NMY27_20235) 4213202..4213975 - 774 WP_007753642.1 cyclic-guanylate-specific phosphodiesterase -
NMY27_RS20260 (NMY27_20240) 4214208..4215140 + 933 WP_275876205.1 sugar kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11684.55 Da        Isoelectric Point: 6.2118

>T252356 WP_105630385.1 NZ_CP101591:c4210721-4210413 [Cronobacter dublinensis]
MQYQIYRNTSTNKKYPYLIDVQSDLIDVLTTRVVIPLVPRFMAQKPLPERMCPVVEVDGDEYIVMTHEMASVGKSVLGEH
AASALPWRQHIKNAIDFVFDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9244.48 Da        Isoelectric Point: 6.4648

>AT252356 WP_199782193.1 NZ_CP101591:c4210962-4210723 [Cronobacter dublinensis]
MNVVVKPPKRTVSVTIDEALYQRARAQGINLSQRLSLVLEEDLRAIERQQWKDENREGLLELNRIADECGHFADEHRKF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References