252325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018989..2019134 Replicon chromosome
Accession NZ_CP101567
Organism Klebsiella pneumoniae subsp. pneumoniae strain KP29

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019025..2019127 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018989..2019134 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMY30_RS09910 (NMY30_09895) 2014119..2016179 + 2061 WP_004151449.1 oligopeptidase B -
NMY30_RS09915 (NMY30_09900) 2016183..2016842 - 660 WP_002911407.1 exodeoxyribonuclease X -
NMY30_RS09920 (NMY30_09905) 2016921..2017151 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NMY30_RS09925 (NMY30_09910) 2017264..2017638 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NMY30_RS09930 (NMY30_09915) 2017642..2018511 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NMY30_RS09935 (NMY30_09920) 2018528..2018866 + 339 WP_002911404.1 YebY family protein -
- 2018989..2019134 - 146 - - Antitoxin
- 2019025..2019127 + 103 - - Toxin
NMY30_RS09940 (NMY30_09925) 2019502..2019645 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NMY30_RS09945 (NMY30_09930) 2019750..2020718 - 969 WP_004151446.1 VirK/YbjX family protein -
NMY30_RS09950 (NMY30_09935) 2020875..2021528 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NMY30_RS09955 (NMY30_09940) 2021525..2021716 - 192 WP_002911395.1 YebW family protein -
NMY30_RS09960 (NMY30_09945) 2021814..2022053 - 240 WP_002911393.1 YebV family protein -
NMY30_RS09965 (NMY30_09950) 2022169..2023602 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252325 NZ_CP101567:2019025-2019127 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252325 NZ_CP101567:c2019134-2018989 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References