Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2099739..2099884 Replicon chromosome
Accession NZ_CP101554
Organism Klebsiella pneumoniae subsp. pneumoniae strain KP72

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2099775..2099877 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2099739..2099884 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMY33_RS10310 (NMY33_10305) 2094869..2096929 + 2061 WP_004151449.1 oligopeptidase B -
NMY33_RS10315 (NMY33_10310) 2096933..2097592 - 660 WP_002911407.1 exodeoxyribonuclease X -
NMY33_RS10320 (NMY33_10315) 2097671..2097901 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NMY33_RS10325 (NMY33_10320) 2098014..2098388 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NMY33_RS10330 (NMY33_10325) 2098392..2099261 + 870 WP_019725445.1 copper homeostasis membrane protein CopD -
NMY33_RS10335 (NMY33_10330) 2099278..2099616 + 339 WP_002911404.1 YebY family protein -
- 2099739..2099884 - 146 - - Antitoxin
- 2099775..2099877 + 103 - - Toxin
NMY33_RS10340 (NMY33_10335) 2100252..2100395 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NMY33_RS10345 (NMY33_10340) 2100500..2101468 - 969 WP_004151446.1 VirK/YbjX family protein -
NMY33_RS10350 (NMY33_10345) 2101625..2102278 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
NMY33_RS10355 (NMY33_10350) 2102275..2102466 - 192 WP_002911395.1 YebW family protein -
NMY33_RS10360 (NMY33_10355) 2102564..2102803 - 240 WP_002911393.1 YebV family protein -
NMY33_RS10365 (NMY33_10360) 2102919..2104352 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252281 NZ_CP101554:2099775-2099877 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252281 NZ_CP101554:c2099884-2099739 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References