Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2050816..2050961 | Replicon | chromosome |
| Accession | NZ_CP101542 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain KP21 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2050852..2050954 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2050816..2050961 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMY29_RS10090 (NMY29_10075) | 2045946..2048006 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NMY29_RS10095 (NMY29_10080) | 2048010..2048669 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NMY29_RS10100 (NMY29_10085) | 2048748..2048978 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NMY29_RS10105 (NMY29_10090) | 2049091..2049465 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NMY29_RS10110 (NMY29_10095) | 2049469..2050338 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| NMY29_RS10115 (NMY29_10100) | 2050355..2050693 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2050816..2050961 | - | 146 | - | - | Antitoxin |
| - | 2050852..2050954 | + | 103 | - | - | Toxin |
| NMY29_RS10120 (NMY29_10105) | 2051329..2051472 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NMY29_RS10125 (NMY29_10110) | 2051577..2052545 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NMY29_RS10130 (NMY29_10115) | 2052702..2053355 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| NMY29_RS10135 (NMY29_10120) | 2053352..2053543 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NMY29_RS10140 (NMY29_10125) | 2053641..2053880 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NMY29_RS10145 (NMY29_10130) | 2053996..2055429 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T252241 NZ_CP101542:2050852-2050954 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT252241 NZ_CP101542:c2050961-2050816 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT