Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 3628387..3628943 Replicon chromosome
Accession NZ_CP101527
Organism Alkalimarinus sediminis strain FA028

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NNL22_RS16130 Protein ID WP_251813107.1
Coordinates 3628387..3628698 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NNL22_RS16135 Protein ID WP_251813108.1
Coordinates 3628686..3628943 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNL22_RS16095 (NNL22_16080) 3623548..3623979 - 432 WP_251813114.1 hypothetical protein -
NNL22_RS16100 (NNL22_16085) 3624110..3624532 - 423 WP_251813113.1 hypothetical protein -
NNL22_RS16105 (NNL22_16090) 3624658..3625215 - 558 WP_267267784.1 hypothetical protein -
NNL22_RS16110 (NNL22_16095) 3626033..3626464 - 432 WP_251813103.1 hypothetical protein -
NNL22_RS16115 (NNL22_16100) 3626592..3626870 - 279 WP_251813104.1 hypothetical protein -
NNL22_RS16120 (NNL22_16105) 3627033..3627401 - 369 WP_251813105.1 hypothetical protein -
NNL22_RS16125 (NNL22_16110) 3627475..3627972 - 498 WP_251813106.1 hypothetical protein -
NNL22_RS16130 (NNL22_16115) 3628387..3628698 - 312 WP_251813107.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NNL22_RS16135 (NNL22_16120) 3628686..3628943 - 258 WP_251813108.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NNL22_RS16140 (NNL22_16125) 3630804..3631247 - 444 WP_251813117.1 hypothetical protein -
NNL22_RS16145 (NNL22_16130) 3632120..3632575 - 456 WP_251813118.1 Imm26 family immunity protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 3622155..3640099 17944


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12146.79 Da        Isoelectric Point: 4.5482

>T252206 WP_251813107.1 NZ_CP101527:c3628698-3628387 [Alkalimarinus sediminis]
MVQIIWTEPALDNLDDIAEYIAVSNPYAAKQLVENVFSKVQRLEQFPDSGRVPEEISNLNYRELVVNPCRVFYKVDRDSV
YILHVMRQERDLRKFLLSTENEN

Download         Length: 312 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9861.47 Da        Isoelectric Point: 7.2034

>AT252206 WP_251813108.1 NZ_CP101527:c3628943-3628686 [Alkalimarinus sediminis]
MRTEVVTTLKRQATKLLADLHESKEPILITEHGQPSAYLLDVADYELMVDRMKILEGIAKGEQAIRDGRTMNMEQAREKM
NKWFK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References