Detailed information of TA system TA252203

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 332097..333537
• Replicon: chromosome
• Accession: NZ_CP101527
• Organism: Alkalimarinus sediminis strain FA028

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: NNL22_RS01540
• Protein ID: WP_251810812.1
• Coordinates: 332097..332984 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: NNL22_RS01545
• Protein ID: WP_251810810.1
• Coordinates: 333013..333537 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NNL22_RS01530 (NNL22_01525)	329046..330986	-	1941	WP_267267819.1	DUF3578 domain-containing protein	-
NNL22_RS01535 (NNL22_01530)	331460..331762	-	303	WP_251810813.1	hypothetical protein	-
NNL22_RS01540 (NNL22_01535)	332097..332984	-	888	WP_251810812.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
NNL22_RS01545 (NNL22_01540)	333013..333537	-	525	WP_251810810.1	hypothetical protein	Antitoxin
NNL22_RS01550 (NNL22_01545)	333616..334989	-	1374	WP_251810808.1	FAD-binding oxidoreductase	-
NNL22_RS01555 (NNL22_01550)	335189..336370	+	1182	WP_251810806.1	AI-2E family transporter	-
NNL22_RS01560 (NNL22_01555)	336499..337131	+	633	WP_251810804.1	guanylate kinase	-
NNL22_RS01565 (NNL22_01560)	337200..337412	+	213	WP_250656452.1	DNA-directed RNA polymerase subunit omega	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-258)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34215.27 Da
• Isoelectric Point: 6.3622

>T252203 WP_251810812.1 NZ_CP101527:c332984-332097 [Alkalimarinus sediminis]
MLKQQIRQIVQENPDYAAVTPVIEKEILHHDIMDVLIKQGAMQQLTFIGGTSLRMCYNSSRLSEDLDFNGGHNFKPSDFE
GLESEIQTYIQNKYETDVWVNKPSDKRQGDTVSWKISIIKEASRPDLPRQKMHIDVCAIPSFDIEKRPLINHYNIVVPTE
GILVPVQSLQEMLADKLIALAYRARRIKPRDIWDIVWIKQRGTNLSKILVEKKLIARQKQTEDFRQALSVQLGKLMSEDE
VRDDFNMEMSRFIPKQTKERTLDNPEYWPYVQGEVNAIVSELLNDKSPKNPFDMG

Nucleotide

• Length: 888 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19274.54 Da
• Isoelectric Point: 9.8012

>AT252203 WP_251810810.1 NZ_CP101527:c333537-333013 [Alkalimarinus sediminis]
MTKSDKLLNALAKAVNAGGGIHSATELAFMLGLPYDPAFRKFLADCVNKGLLRRVMKGLYESAITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIELTHTKKPVEKIAPNLYYDPDIKMYRAHKAQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp