Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2329710..2330296 Replicon plasmid pla_1
Accession NZ_CP101525
Organism Burkholderia arboris strain MEC_B345

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NLX30_RS28940 Protein ID WP_234743364.1
Coordinates 2329913..2330296 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NLX30_RS28935 Protein ID WP_234743363.1
Coordinates 2329710..2329916 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX30_RS28910 (NLX30_28865) 2325028..2325861 - 834 WP_212103873.1 DUF1295 domain-containing protein -
NLX30_RS28915 (NLX30_28870) 2326013..2326747 - 735 WP_059676247.1 anti-sigma factor -
NLX30_RS28920 (NLX30_28875) 2326744..2327355 - 612 WP_034203526.1 sigma-70 family RNA polymerase sigma factor -
NLX30_RS28925 (NLX30_28880) 2327606..2328175 + 570 WP_212103891.1 lipocalin family protein -
NLX30_RS28930 (NLX30_28885) 2328466..2329125 - 660 WP_059676244.1 carbonic anhydrase -
NLX30_RS28935 (NLX30_28890) 2329710..2329916 + 207 WP_234743363.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NLX30_RS28940 (NLX30_28895) 2329913..2330296 + 384 WP_234743364.1 PIN domain-containing protein Toxin
NLX30_RS28945 (NLX30_28900) 2330340..2330591 + 252 WP_234743365.1 hypothetical protein -
NLX30_RS28950 (NLX30_28905) 2330588..2330791 - 204 Protein_2124 transposase domain-containing protein -
NLX30_RS28955 (NLX30_28910) 2331409..2332281 - 873 WP_027792660.1 slipin family protein -
NLX30_RS28960 (NLX30_28915) 2332609..2333061 + 453 WP_011548845.1 type II toxin-antitoxin system HicB family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / adeG / pchB / pchD / pmlI/bspI1 / pmlR/bspR1 / hsiC1/vipB / flgE / gnd 1..3525317 3525317


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-114)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14289.65 Da        Isoelectric Point: 7.7835

>T252201 WP_234743364.1 NZ_CP101525:2329913-2330296 [Burkholderia arboris]
MSVLVDTSVWVEHFRRPLPALIQLLRVDSILTHPLVILELTCGTPPEPRARTLGDLALLRQTRLATPGEVADWIERERLY
GRGCGAVDCTLLASVLLTPSTRLWTRDRRLAQLAERFGAQYVPPDLH

Download         Length: 384 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7297.36 Da        Isoelectric Point: 6.2465

>AT252201 WP_234743363.1 NZ_CP101525:2329710-2329916 [Burkholderia arboris]
MRTTVTVDDTLYARALELAEPGMPPADLFRAALETFVRVQAGQRLAALGGRAPDMADVPRRAAEATAR

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References