Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 1965705..1966381 Replicon chromosome
Accession NZ_CP101524
Organism Burkholderia arboris strain MEC_B345

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag NLX30_RS09570 Protein ID WP_256084842.1
Coordinates 1965965..1966381 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NLX30_RS09565 Protein ID WP_256084841.1
Coordinates 1965705..1965968 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX30_RS09550 (NLX30_09545) 1961248..1963512 + 2265 WP_174991472.1 TonB-dependent siderophore receptor -
NLX30_RS09555 (NLX30_09550) 1963599..1964438 + 840 WP_059234249.1 N(5)-hydroxyornithine transformylase PvdF -
NLX30_RS09560 (NLX30_09555) 1964438..1965454 + 1017 WP_256084840.1 GNAT family N-acetyltransferase -
NLX30_RS09565 (NLX30_09560) 1965705..1965968 + 264 WP_256084841.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NLX30_RS09570 (NLX30_09565) 1965965..1966381 + 417 WP_256084842.1 PIN domain-containing protein Toxin
NLX30_RS09575 (NLX30_09570) 1966558..1967721 + 1164 WP_174991477.1 M20 aminoacylase family protein -
NLX30_RS09580 (NLX30_09575) 1967887..1968426 + 540 WP_256084843.1 outer membrane protein assembly factor BamE -
NLX30_RS09585 (NLX30_09580) 1968453..1969757 - 1305 WP_256084844.1 cobyrinate a,c-diamide synthase -
NLX30_RS09590 (NLX30_09585) 1969760..1970362 - 603 WP_059234234.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
NLX30_RS09595 (NLX30_09590) 1970397..1970774 - 378 WP_059234232.1 cobalamin biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-130)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14499.68 Da        Isoelectric Point: 8.5418

>T252197 WP_256084842.1 NZ_CP101524:1965965-1966381 [Burkholderia arboris]
VTTLYMLDTNICSFIMRERPPVVLSRLQSCVNAQHRIVVSAITYAEMRFGAVGKKASPKHAELVTAFVSRLDGVLPWDTA
AVDATAAIRADLAARGTPIGTNDASIAGHAIAAGAVLVSHNGRAFGRVAGLSLEDWAA

Download         Length: 417 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9821.08 Da        Isoelectric Point: 4.5112

>AT252197 WP_256084841.1 NZ_CP101524:1965705-1965968 [Burkholderia arboris]
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFANELLADADFLAERPAVIESGRFDLSGDAD
APTESSR

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References