Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-vagC/VapC-VagC
Location 154457..155094 Replicon chromosome
Accession NZ_CP101524
Organism Burkholderia arboris strain MEC_B345

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NLX30_RS00690 Protein ID WP_256085429.1
Coordinates 154693..155094 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NLX30_RS00685 Protein ID WP_059236527.1
Coordinates 154457..154693 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLX30_RS00670 (NLX30_00670) 150173..151207 + 1035 WP_059232772.1 helix-turn-helix domain-containing protein -
NLX30_RS00675 (NLX30_00675) 151298..152404 - 1107 WP_256086028.1 ADP-heptose--LPS heptosyltransferase -
NLX30_RS00680 (NLX30_00680) 152401..154104 - 1704 WP_256085428.1 thiamine pyrophosphate-binding protein -
NLX30_RS00685 (NLX30_00685) 154457..154693 + 237 WP_059236527.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NLX30_RS00690 (NLX30_00690) 154693..155094 + 402 WP_256085429.1 type II toxin-antitoxin system VapC family toxin Toxin
NLX30_RS00695 (NLX30_00695) 155164..156552 - 1389 WP_059232769.1 L-serine ammonia-lyase -
NLX30_RS00700 (NLX30_00700) 156583..157725 - 1143 WP_256085430.1 alginate lyase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14964.06 Da        Isoelectric Point: 5.6634

>T252196 WP_256085429.1 NZ_CP101524:154693-155094 [Burkholderia arboris]
MPRYMLDTNMCIYLIKNQPEQVARRFAQCYSGDVVMSAITHAELEYGVAACANPVRERRNLAALIEDIPVAPFDTAAAQA
YGPVREATRERKKDHLDKLIAAHAVSLDVVLVTNNERDFASYPGLRLENWLND

Download         Length: 402 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8996.03 Da        Isoelectric Point: 5.1585

>AT252196 WP_059236527.1 NZ_CP101524:154457-154693 [Burkholderia arboris]
VHTTRVFRNGNSQAVRIPADLAYERSDMELEIERVGDEIRIRPTRRPLTHVLEKFANFGPDFMAEGRGDQEQAEREGL

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References