Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 1664198..1664881 Replicon chromosome
Accession NZ_CP101497
Organism Microcella sp. MMS21-STM10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NNL39_RS08080 Protein ID WP_255158702.1
Coordinates 1664495..1664881 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NNL39_RS08075 Protein ID WP_255158701.1
Coordinates 1664198..1664494 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNL39_RS08065 (NNL39_08065) 1661351..1662334 + 984 WP_255158698.1 ribonucleotide-diphosphate reductase subunit beta -
NNL39_RS08070 (NNL39_08070) 1662377..1664146 + 1770 WP_255158700.1 amidohydrolase -
NNL39_RS08075 (NNL39_08075) 1664198..1664494 + 297 WP_255158701.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NNL39_RS08080 (NNL39_08080) 1664495..1664881 + 387 WP_255158702.1 type II toxin-antitoxin system VapC family toxin Toxin
NNL39_RS08085 (NNL39_08085) 1664911..1665882 + 972 WP_255158703.1 acyl-CoA thioesterase -
NNL39_RS08090 (NNL39_08090) 1665952..1667037 + 1086 WP_255158704.1 hypothetical protein -
NNL39_RS08095 (NNL39_08095) 1667061..1667294 - 234 WP_255158705.1 DUF3418 domain-containing protein -
NNL39_RS08100 (NNL39_08100) 1667293..1668921 + 1629 WP_255158707.1 CDP-alcohol phosphatidyltransferase -
NNL39_RS08105 (NNL39_08105) 1668905..1669315 - 411 WP_255158709.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-114)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13712.75 Da        Isoelectric Point: 4.6647

>T252160 WP_255158702.1 NZ_CP101497:1664495-1664881 [Microcella sp. MMS21-STM10]
VLYLDTSAAVKLLIEEKESSALRAYLSHHDWASSALVRTELVRALLRADPSVVPRALDLLAQGNLLVIDTQVLDTAARLS
PPSLRSLDAIHLASALELRDELTAFVAYDERLLAAASALGMPVASPAD

Download         Length: 387 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10907.34 Da        Isoelectric Point: 5.8946

>AT252160 WP_255158701.1 NZ_CP101497:1664198-1664494 [Microcella sp. MMS21-STM10]
MDRIGVRELRQNASKYLDRVKQGESIEVTERGVPVAIIGPVPTVKDSRVQELIDERRMTPGRGGSAAWLAANPPTPINPE
HGRPSIADLLDEQREERL

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References