Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 3043319..3043883 Replicon chromosome
Accession NZ_CP101464
Organism Janibacter sp. CX7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMQ01_RS14980 Protein ID WP_255184697.1
Coordinates 3043319..3043666 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NMQ01_RS14985 Protein ID WP_255184698.1
Coordinates 3043653..3043883 (-) Length 77 a.a.

Genomic Context

NMQ01_RS14960NMQ01_RS14965NMQ01_RS14995NMQ01_RS15000NMQ01_RS14970NMQ01_RS14975NMQ01_RS14980NMQ01_RS14985NMQ01_RS15005NMQ01_RS15010NMQ01_RS15015
Location: 3039330..3040442 (1113 bp)
Type: Others
Protein ID: WP_255184693.1
Location: 3040486..3041760 (1275 bp)
Type: Others
Protein ID: WP_255184694.1
Location: 3044094..3045446 (1353 bp)
Type: Others
Protein ID: WP_255184699.1
Location: 3045443..3047311 (1869 bp)
Type: Others
Protein ID: WP_255184700.1
Location: 3041902..3042294 (393 bp)
Type: Others
Protein ID: WP_255184695.1
Location: 3042291..3043292 (1002 bp)
Type: Others
Protein ID: WP_255184696.1
Location: 3043319..3043666 (348 bp)
Type: Toxin
Protein ID: WP_255184697.1
Location: 3043653..3043883 (231 bp)
Type: Antitoxin
Protein ID: WP_255184698.1
Location: 3047308..3047706 (399 bp)
Type: Others
Protein ID: WP_255184701.1
Location: 3047703..3047963 (261 bp)
Type: Others
Protein ID: WP_072625853.1
Location: 3047986..3048459 (474 bp)
Type: Others
Protein ID: WP_255184702.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMQ01_RS14960 (NMQ01_14920)3039330..3040442+1113WP_255184693.1polysulfide reductase NrfD-
NMQ01_RS14965 (NMQ01_14925)3040486..3041760+1275WP_255184694.1OFA family MFS transporter-
NMQ01_RS14970 (NMQ01_14930)3041902..3042294-393WP_255184695.1rhodanese-like domain-containing protein-
NMQ01_RS14975 (NMQ01_14935)3042291..3043292-1002WP_255184696.1selenide, water dikinase SelD-
NMQ01_RS14980 (NMQ01_14940)3043319..3043666-348WP_255184697.1type II toxin-antitoxin system PemK/MazF family toxinToxin
NMQ01_RS14985 (NMQ01_14945)3043653..3043883-231WP_255184698.1ribbon-helix-helix domain-containing proteinAntitoxin
NMQ01_RS14995 (NMQ01_14955)3044094..3045446+1353WP_255184699.1L-seryl-tRNA(Sec) selenium transferase-
NMQ01_RS15000 (NMQ01_14960)3045443..3047311+1869WP_255184700.1SelB C-terminal domain-containing protein-
NMQ01_RS15005 (NMQ01_14965)3047308..3047706-399WP_255184701.1type II toxin-antitoxin system VapC family toxin-
NMQ01_RS15010 (NMQ01_14970)3047703..3047963-261WP_072625853.1type II toxin-antitoxin system prevent-host-death family antitoxin-
NMQ01_RS15015 (NMQ01_14975)3047986..3048459-474WP_255184702.1OsmC family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-38)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12405.33 Da        Isoelectric Point: 11.1401

>T252149 WP_255184697.1 NZ_CP101464:c3043666-3043319 [Janibacter sp. CX7]
MLRGEIRLADLDPVRGSEAAKRRPVLVVSNDVANRSAVRRGRGVVTVVPLTSNTERIFAFQAMLPADRTGLSLDSKAQAE
QVRAIDVQRLGGVIGRVPAALLDEVDDALRLHLGL

Download         Length: 348 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8173.98 Da        Isoelectric Point: 4.0713

>AT252149 WP_255184698.1 NZ_CP101464:c3043883-3043653 [Janibacter sp. CX7]
MKISVSLPDEDVALLDEVAREEGLSSRSAALHRAVELLRLRGLEVHYDEAWAEWQAAGDADAWDGVAGDGLGDAAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References