Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 3043319..3043883 Replicon chromosome
Accession NZ_CP101464
Organism Janibacter sp. CX7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMQ01_RS14980 Protein ID WP_255184697.1
Coordinates 3043319..3043666 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NMQ01_RS14985 Protein ID WP_255184698.1
Coordinates 3043653..3043883 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMQ01_RS14960 (NMQ01_14920) 3039330..3040442 + 1113 WP_255184693.1 polysulfide reductase NrfD -
NMQ01_RS14965 (NMQ01_14925) 3040486..3041760 + 1275 WP_255184694.1 OFA family MFS transporter -
NMQ01_RS14970 (NMQ01_14930) 3041902..3042294 - 393 WP_255184695.1 rhodanese-like domain-containing protein -
NMQ01_RS14975 (NMQ01_14935) 3042291..3043292 - 1002 WP_255184696.1 selenide, water dikinase SelD -
NMQ01_RS14980 (NMQ01_14940) 3043319..3043666 - 348 WP_255184697.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NMQ01_RS14985 (NMQ01_14945) 3043653..3043883 - 231 WP_255184698.1 ribbon-helix-helix domain-containing protein Antitoxin
NMQ01_RS14995 (NMQ01_14955) 3044094..3045446 + 1353 WP_255184699.1 L-seryl-tRNA(Sec) selenium transferase -
NMQ01_RS15000 (NMQ01_14960) 3045443..3047311 + 1869 WP_255184700.1 SelB C-terminal domain-containing protein -
NMQ01_RS15005 (NMQ01_14965) 3047308..3047706 - 399 WP_255184701.1 type II toxin-antitoxin system VapC family toxin -
NMQ01_RS15010 (NMQ01_14970) 3047703..3047963 - 261 WP_072625853.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
NMQ01_RS15015 (NMQ01_14975) 3047986..3048459 - 474 WP_255184702.1 OsmC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-38)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12405.33 Da        Isoelectric Point: 11.1401

>T252149 WP_255184697.1 NZ_CP101464:c3043666-3043319 [Janibacter sp. CX7]
MLRGEIRLADLDPVRGSEAAKRRPVLVVSNDVANRSAVRRGRGVVTVVPLTSNTERIFAFQAMLPADRTGLSLDSKAQAE
QVRAIDVQRLGGVIGRVPAALLDEVDDALRLHLGL

Download         Length: 348 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8173.98 Da        Isoelectric Point: 4.0713

>AT252149 WP_255184698.1 NZ_CP101464:c3043883-3043653 [Janibacter sp. CX7]
MKISVSLPDEDVALLDEVAREEGLSSRSAALHRAVELLRLRGLEVHYDEAWAEWQAAGDADAWDGVAGDGLGDAAR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References