Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 2900339..2900880 Replicon chromosome
Accession NZ_CP101464
Organism Janibacter sp. CX7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NMQ01_RS14290 Protein ID WP_255184568.1
Coordinates 2900602..2900880 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NMQ01_RS14285 Protein ID WP_255184567.1
Coordinates 2900339..2900605 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMQ01_RS14260 (NMQ01_14220) 2895377..2896399 - 1023 WP_255184562.1 DnaJ C-terminal domain-containing protein -
NMQ01_RS14265 (NMQ01_14225) 2896424..2897101 - 678 WP_255184563.1 nucleotide exchange factor GrpE -
NMQ01_RS14270 (NMQ01_14230) 2897098..2898984 - 1887 WP_255184564.1 molecular chaperone DnaK -
NMQ01_RS14275 (NMQ01_14235) 2899330..2899686 + 357 WP_255184565.1 hypothetical protein -
NMQ01_RS14280 (NMQ01_14240) 2899694..2900275 - 582 WP_255184566.1 TIGR03086 family metal-binding protein -
NMQ01_RS14285 (NMQ01_14245) 2900339..2900605 + 267 WP_255184567.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NMQ01_RS14290 (NMQ01_14250) 2900602..2900880 + 279 WP_255184568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NMQ01_RS14295 (NMQ01_14255) 2900885..2901595 - 711 WP_255184569.1 spermidine synthase -
NMQ01_RS14300 (NMQ01_14260) 2901697..2903061 + 1365 WP_255184570.1 potassium transporter TrkG -
NMQ01_RS14305 (NMQ01_14265) 2903054..2903461 + 408 WP_255184571.1 NAD-binding protein -
NMQ01_RS14310 (NMQ01_14270) 2903574..2904452 - 879 WP_255184572.1 helix-turn-helix transcriptional regulator -
NMQ01_RS14315 (NMQ01_14275) 2904631..2905254 + 624 WP_255184573.1 papain-like cysteine protease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(32-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10217.74 Da        Isoelectric Point: 10.0208

>T252148 WP_255184568.1 NZ_CP101464:2900602-2900880 [Janibacter sp. CX7]
MSDATYELVVAPPAARAIRDDLPESVTAAVIEFITGALIAHPRRVGKPLRADLAGIHSARRGTYRVLYRINDSAQEVLVL
RIDHRRDVYRPG

Download         Length: 279 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9752.86 Da        Isoelectric Point: 4.4698

>AT252148 WP_255184567.1 NZ_CP101464:2900339-2900605 [Janibacter sp. CX7]
MSIEPLREVRNHFSDVVDRVEREHERVTVTRNGRAVAVVISPDDLSELEETLAVLSDADALADIREADAAYRSGDVVRGV
EAVRALRP

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References