Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
| Location | 896668..897236 | Replicon | chromosome |
| Accession | NZ_CP101464 | ||
| Organism | Janibacter sp. CX7 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | - |
| Locus tag | NMQ01_RS04445 | Protein ID | WP_255185663.1 |
| Coordinates | 896910..897236 (+) | Length | 109 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | - |
| Locus tag | NMQ01_RS04440 | Protein ID | WP_255185662.1 |
| Coordinates | 896668..896907 (+) | Length | 80 a.a. |
Genomic Context
Location: 892558..893469 (912 bp)
Type: Others
Protein ID: WP_255185658.1
Type: Others
Protein ID: WP_255185658.1
Location: 893721..893978 (258 bp)
Type: Others
Protein ID: Protein_867
Type: Others
Protein ID: Protein_867
Location: 893999..894940 (942 bp)
Type: Others
Protein ID: WP_255185659.1
Type: Others
Protein ID: WP_255185659.1
Location: 895629..896633 (1005 bp)
Type: Others
Protein ID: WP_255185661.1
Type: Others
Protein ID: WP_255185661.1
Location: 896668..896907 (240 bp)
Type: Antitoxin
Protein ID: WP_255185662.1
Type: Antitoxin
Protein ID: WP_255185662.1
Location: 896910..897236 (327 bp)
Type: Toxin
Protein ID: WP_255185663.1
Type: Toxin
Protein ID: WP_255185663.1
Location: 897268..898452 (1185 bp)
Type: Others
Protein ID: WP_255185664.1
Type: Others
Protein ID: WP_255185664.1
Location: 898452..899567 (1116 bp)
Type: Others
Protein ID: WP_255186321.1
Type: Others
Protein ID: WP_255186321.1
Location: 899564..900541 (978 bp)
Type: Others
Protein ID: WP_255185665.1
Type: Others
Protein ID: WP_255185665.1
Location: 894963..895523 (561 bp)
Type: Others
Protein ID: WP_255185660.1
Type: Others
Protein ID: WP_255185660.1
Location: 900672..902171 (1500 bp)
Type: Others
Protein ID: WP_255185666.1
Type: Others
Protein ID: WP_255185666.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMQ01_RS04415 (NMQ01_04400) | 892558..893469 | + | 912 | WP_255185658.1 | hypothetical protein | - |
| NMQ01_RS04420 (NMQ01_04405) | 893721..893978 | + | 258 | Protein_867 | metalloregulator ArsR/SmtB family transcription factor | - |
| NMQ01_RS04425 (NMQ01_04410) | 893999..894940 | + | 942 | WP_255185659.1 | cation diffusion facilitator family transporter | - |
| NMQ01_RS04430 (NMQ01_04415) | 894963..895523 | - | 561 | WP_255185660.1 | TetR/AcrR family transcriptional regulator | - |
| NMQ01_RS04435 (NMQ01_04420) | 895629..896633 | + | 1005 | WP_255185661.1 | ABC transporter permease | - |
| NMQ01_RS04440 (NMQ01_04425) | 896668..896907 | + | 240 | WP_255185662.1 | antitoxin MazE5 | Antitoxin |
| NMQ01_RS04445 (NMQ01_04430) | 896910..897236 | + | 327 | WP_255185663.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| NMQ01_RS04450 (NMQ01_04435) | 897268..898452 | + | 1185 | WP_255185664.1 | cysteine desulfurase family protein | - |
| NMQ01_RS04455 (NMQ01_04440) | 898452..899567 | + | 1116 | WP_255186321.1 | tRNA 2-thiouridine(34) synthase MnmA | - |
| NMQ01_RS04460 (NMQ01_04445) | 899564..900541 | + | 978 | WP_255185665.1 | methionine synthase | - |
| NMQ01_RS04465 (NMQ01_04450) | 900672..902171 | - | 1500 | WP_255185666.1 | long-chain fatty acid--CoA ligase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 109 a.a. Molecular weight: 11339.13 Da Isoelectric Point: 5.1205
>T252147 WP_255185663.1 NZ_CP101464:896910-897236 [Janibacter sp. CX7]
VALPARGELWWADLADAGARPVVVLSRGAAIAGRRRTLVAPCSTVVRDLPSEVLLEPGEEPVDRLCAAQLDAVTDLPVAL
LTRRLGRLSDEAVRRLCAALGVATGCSD
VALPARGELWWADLADAGARPVVVLSRGAAIAGRRRTLVAPCSTVVRDLPSEVLLEPGEEPVDRLCAAQLDAVTDLPVAL
LTRRLGRLSDEAVRRLCAALGVATGCSD
Download Length: 327 bp