Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 896668..897236 Replicon chromosome
Accession NZ_CP101464
Organism Janibacter sp. CX7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMQ01_RS04445 Protein ID WP_255185663.1
Coordinates 896910..897236 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NMQ01_RS04440 Protein ID WP_255185662.1
Coordinates 896668..896907 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMQ01_RS04415 (NMQ01_04400) 892558..893469 + 912 WP_255185658.1 hypothetical protein -
NMQ01_RS04420 (NMQ01_04405) 893721..893978 + 258 Protein_867 metalloregulator ArsR/SmtB family transcription factor -
NMQ01_RS04425 (NMQ01_04410) 893999..894940 + 942 WP_255185659.1 cation diffusion facilitator family transporter -
NMQ01_RS04430 (NMQ01_04415) 894963..895523 - 561 WP_255185660.1 TetR/AcrR family transcriptional regulator -
NMQ01_RS04435 (NMQ01_04420) 895629..896633 + 1005 WP_255185661.1 ABC transporter permease -
NMQ01_RS04440 (NMQ01_04425) 896668..896907 + 240 WP_255185662.1 antitoxin MazE5 Antitoxin
NMQ01_RS04445 (NMQ01_04430) 896910..897236 + 327 WP_255185663.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NMQ01_RS04450 (NMQ01_04435) 897268..898452 + 1185 WP_255185664.1 cysteine desulfurase family protein -
NMQ01_RS04455 (NMQ01_04440) 898452..899567 + 1116 WP_255186321.1 tRNA 2-thiouridine(34) synthase MnmA -
NMQ01_RS04460 (NMQ01_04445) 899564..900541 + 978 WP_255185665.1 methionine synthase -
NMQ01_RS04465 (NMQ01_04450) 900672..902171 - 1500 WP_255185666.1 long-chain fatty acid--CoA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11339.13 Da        Isoelectric Point: 5.1205

>T252147 WP_255185663.1 NZ_CP101464:896910-897236 [Janibacter sp. CX7]
VALPARGELWWADLADAGARPVVVLSRGAAIAGRRRTLVAPCSTVVRDLPSEVLLEPGEEPVDRLCAAQLDAVTDLPVAL
LTRRLGRLSDEAVRRLCAALGVATGCSD

Download         Length: 327 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8627.53 Da        Isoelectric Point: 4.8053

>AT252147 WP_255185662.1 NZ_CP101464:896668-896907 [Janibacter sp. CX7]
MAKVRVSTTVDADLLERARAAHGAATDASLVEASLQALLRTHRAAEIDEAYRRAYREAPADLSDDWGDLGSFLDEAARR

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References