Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2768471..2768976 Replicon chromosome
Accession NZ_CP101417
Organism Xanthomonas hortorum strain jj2001

Toxin (Protein)


Gene name relE Uniprot ID V7ZHE2
Locus tag NMB96_RS11915 Protein ID WP_023902910.1
Coordinates 2768471..2768728 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6V7E8M0
Locus tag NMB96_RS11920 Protein ID WP_043888988.1
Coordinates 2768725..2768976 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMB96_RS11890 (NMB96_11875) 2764169..2765524 + 1356 WP_023902907.1 aminodeoxychorismate synthase component I -
NMB96_RS11895 (NMB96_11880) 2765540..2766649 + 1110 WP_043888987.1 endolytic transglycosylase MltG -
NMB96_RS11900 (NMB96_11885) 2766646..2767605 + 960 WP_183086860.1 DNA polymerase III subunit delta' -
NMB96_RS11905 (NMB96_11890) 2767602..2767955 + 354 WP_003483889.1 PilZ domain-containing protein -
NMB96_RS11915 (NMB96_11900) 2768471..2768728 - 258 WP_023902910.1 Txe/YoeB family addiction module toxin Toxin
NMB96_RS11920 (NMB96_11905) 2768725..2768976 - 252 WP_043888988.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NMB96_RS11925 (NMB96_11910) 2769162..2769488 + 327 WP_255084930.1 hypothetical protein -
NMB96_RS11930 (NMB96_11915) 2769729..2771330 - 1602 WP_255084931.1 propionate catabolism operon regulatory protein PrpR -
NMB96_RS11935 (NMB96_11920) 2771477..2772373 + 897 WP_043888989.1 methylisocitrate lyase -
NMB96_RS11940 (NMB96_11925) 2772449..2773603 + 1155 WP_255084932.1 2-methylcitrate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10170.68 Da        Isoelectric Point: 9.6587

>T252144 WP_023902910.1 NZ_CP101417:c2768728-2768471 [Xanthomonas hortorum]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9269.50 Da        Isoelectric Point: 4.6536

>AT252144 WP_043888988.1 NZ_CP101417:c2768976-2768725 [Xanthomonas hortorum]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7E8N0

Antitoxin

Source ID Structure
AlphaFold DB A0A6V7E8M0

References