Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1906719..1907084 Replicon chromosome
Accession NZ_CP101417
Organism Xanthomonas hortorum strain jj2001

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag NMB96_RS07955 Protein ID WP_006451341.1
Coordinates 1906950..1907084 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag NMB96_RS07950 Protein ID WP_006451340.1
Coordinates 1906719..1906871 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMB96_RS07925 (NMB96_07910) 1902787..1903329 - 543 WP_255086629.1 GTPase -
NMB96_RS07930 (NMB96_07915) 1903326..1904243 - 918 WP_255086630.1 hypothetical protein -
NMB96_RS07935 (NMB96_07920) 1904337..1904696 - 360 WP_006452081.1 hypothetical protein -
NMB96_RS07940 (NMB96_07925) 1904760..1905212 - 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
NMB96_RS07945 (NMB96_07930) 1905686..1906609 + 924 WP_023905530.1 arginase -
NMB96_RS07950 (NMB96_07935) 1906719..1906871 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
NMB96_RS07955 (NMB96_07940) 1906950..1907084 + 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
NMB96_RS07960 (NMB96_07945) 1907327..1907536 + 210 WP_006451342.1 CsbD family protein -
NMB96_RS07965 (NMB96_07950) 1907709..1908998 + 1290 WP_255086631.1 tryptophan--tRNA ligase -
NMB96_RS07970 (NMB96_07955) 1909157..1910143 + 987 WP_255086632.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T252143 WP_006451341.1 NZ_CP101417:1906950-1907084 [Xanthomonas hortorum]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT252143 WP_006451340.1 NZ_CP101417:1906719-1906871 [Xanthomonas hortorum]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References