Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1528906..1529573 Replicon chromosome
Accession NZ_CP101417
Organism Xanthomonas hortorum strain jj2001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NMB96_RS06490 Protein ID WP_255086519.1
Coordinates 1528906..1529322 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NMB96_RS06495 Protein ID WP_255086520.1
Coordinates 1529319..1529573 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMB96_RS06455 (NMB96_06440) 1523942..1525567 - 1626 WP_255086518.1 alpha/beta hydrolase-fold protein -
NMB96_RS06460 (NMB96_06445) 1525933..1526115 + 183 WP_006448384.1 helix-turn-helix transcriptional regulator -
NMB96_RS06465 (NMB96_06450) 1526483..1526668 + 186 Protein_1273 hypothetical protein -
NMB96_RS06470 (NMB96_06455) 1526726..1527178 + 453 WP_183086946.1 hypothetical protein -
NMB96_RS06475 (NMB96_06460) 1527165..1527602 - 438 WP_023905887.1 DUF6393 family protein -
NMB96_RS06480 (NMB96_06465) 1527741..1527911 + 171 WP_192824376.1 hypothetical protein -
NMB96_RS06485 (NMB96_06470) 1528220..1528780 + 561 WP_023905791.1 hypothetical protein -
NMB96_RS06490 (NMB96_06475) 1528906..1529322 - 417 WP_255086519.1 type II toxin-antitoxin system VapC family toxin Toxin
NMB96_RS06495 (NMB96_06480) 1529319..1529573 - 255 WP_255086520.1 Arc family DNA-binding protein Antitoxin
NMB96_RS06500 (NMB96_06485) 1529713..1530825 - 1113 WP_255086521.1 type II toxin-antitoxin system RelE/ParE family toxin -
NMB96_RS06505 (NMB96_06490) 1530812..1531018 - 207 WP_023905787.1 hypothetical protein -
NMB96_RS06510 (NMB96_06495) 1531299..1531805 + 507 WP_043889571.1 hypothetical protein -
NMB96_RS06515 (NMB96_06500) 1531872..1533137 - 1266 WP_023905785.1 phospholipase D-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1494518..1536315 41797


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-41)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14824.09 Da        Isoelectric Point: 5.1239

>T252142 WP_255086519.1 NZ_CP101417:c1529322-1528906 [Xanthomonas hortorum]
VILLDTNVISELWRPRPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPEGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFATLASKARTAGLTLGRADAYIAATAAAQGLAVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9130.49 Da        Isoelectric Point: 10.7495

>AT252142 WP_255086520.1 NZ_CP101417:c1529573-1529319 [Xanthomonas hortorum]
MPSFTVRNIPDDVHRAIRARAARHGRSTEAEIRAILESAAKPADRVKLGSLLVDIGRDAGLTAKQADAFDKLRDKAAIKP
IDLT

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References