Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 3482547..3483132 Replicon chromosome
Accession NZ_CP101416
Organism Pseudanabaena sp. Chao 1811

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMG48_RS15975 Protein ID WP_271252458.1
Coordinates 3482547..3482915 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NMG48_RS15980 Protein ID WP_271252459.1
Coordinates 3482908..3483132 (-) Length 75 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG48_RS15955 3478752..3479222 + 471 WP_271252455.1 hypothetical protein -
NMG48_RS15965 3479581..3480801 + 1221 WP_271252456.1 DUF4336 domain-containing protein -
NMG48_RS15970 3480798..3482363 - 1566 WP_271252457.1 cytochrome P450 -
NMG48_RS15975 3482547..3482915 - 369 WP_271252458.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NMG48_RS15980 3482908..3483132 - 225 WP_271252459.1 hypothetical protein Antitoxin
NMG48_RS15985 3483384..3483935 + 552 WP_271252460.1 transposase -
NMG48_RS15990 3484110..3485489 - 1380 WP_271252461.1 response regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-116)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 123 a.a.        Molecular weight: 13779.80 Da        Isoelectric Point: 8.9293

>T252140 WP_271252458.1 NZ_CP101416:c3482915-3482547 [Pseudanabaena sp. Chao 1811]
MPNGTLTYKRGEIWWVDLNPTIGSETDKERPCLILQNDIGNQNGLTIIVAPLLPNKKTYPFVVNVVPTPKNGLSGDRHIN
LSQMRSVDARRIKNKQGVLEDIYWKEIEKAVSIELGFNNFSS

Download         Length: 369 bp


Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8563.63 Da        Isoelectric Point: 4.0834

>AT252140 WP_271252459.1 NZ_CP101416:c3483132-3482908 [Pseudanabaena sp. Chao 1811]
MSKKVSITLDDEVLSFVDRLASNRSSFINDILLKEKERIFIKELEDAYKEQANDPIFQEEISVWDITVEDGLNA

Download         Length: 225 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References