Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/AbrB(antitoxin)
Location 960936..961518 Replicon chromosome
Accession NZ_CP101416
Organism Pseudanabaena sp. Chao 1811

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMG48_RS04560 Protein ID WP_271254179.1
Coordinates 961168..961518 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NMG48_RS04555 Protein ID WP_271254178.1
Coordinates 960936..961178 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG48_RS04535 956668..957453 + 786 WP_271254175.1 DUF3120 domain-containing protein -
NMG48_RS04540 957666..959096 - 1431 WP_271254176.1 MFS transporter -
NMG48_RS04545 959835..960164 + 330 WP_126388501.1 thioredoxin -
NMG48_RS04550 960331..960879 + 549 WP_271254177.1 bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR -
NMG48_RS04555 960936..961178 + 243 WP_271254178.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NMG48_RS04560 961168..961518 + 351 WP_271254179.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NMG48_RS04565 961546..962319 - 774 WP_271254180.1 precorrin-4 C(11)-methyltransferase -
NMG48_RS04570 962427..963470 - 1044 WP_271254181.1 cobalt-precorrin-5B (C(1))-methyltransferase CbiD -
NMG48_RS04575 963530..965143 - 1614 WP_271254182.1 SpoIID/LytB domain-containing protein -
NMG48_RS04580 965341..966411 - 1071 WP_271254183.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-110)

Antitoxin

PrlF antitoxin

(10-51)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12832.91 Da        Isoelectric Point: 8.7036

>T252137 WP_271254179.1 NZ_CP101416:961168-961518 [Pseudanabaena sp. Chao 1811]
VTFNQFDVVIVPFPFTDTASTKRRPALVISDHVTFNAPTNRSVMAMITTAKHSSWVLDVNILDLPSAGLTYPSIIRMKLF
TLDDVLVIKRIGALSQADRTATQEAIAQLFRLSLEA

Download         Length: 351 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9032.25 Da        Isoelectric Point: 4.3623

>AT252137 WP_271254178.1 NZ_CP101416:960936-961178 [Pseudanabaena sp. Chao 1811]
MQTTQKILASKVTSKFQATIPQSIRNAMGISQGDIVVFEIEEGRVFIKKLQPLNLDYLNAVSETLSEWASPEDEEAYRDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References