Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 433612..434326 Replicon chromosome
Accession NZ_CP101416
Organism Pseudanabaena sp. Chao 1811

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NMG48_RS02030 Protein ID WP_271253777.1
Coordinates 433955..434326 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NMG48_RS02025 Protein ID WP_271253776.1
Coordinates 433612..433941 (-) Length 110 a.a.

Genomic Context

NMG48_RS01990NMG48_RS01995NMG48_RS02015NMG48_RS02035NMG48_RS02050NMG48_RS02055NMG48_RS02000NMG48_RS02005NMG48_RS02010NMG48_RS02020NMG48_RS02025NMG48_RS02030NMG48_RS02040
Location: 429290..429940 (651 bp)
Type: Others
Protein ID: WP_271253772.1
Location: 429959..430198 (240 bp)
Type: Others
Protein ID: WP_271253773.1
Location: 431780..432991 (1212 bp)
Type: Others
Protein ID: WP_271251719.1
Location: 434728..434820 (93 bp)
Type: Others
Protein ID: Protein_401
Location: 436018..438276 (2259 bp)
Type: Others
Protein ID: WP_271253779.1
Location: 438383..439168 (786 bp)
Type: Others
Protein ID: WP_271253780.1
Location: 430282..430563 (282 bp)
Type: Others
Protein ID: WP_271253774.1
Location: 430550..430834 (285 bp)
Type: Others
Protein ID: WP_271253775.1
Location: 430967..431698 (732 bp)
Type: Others
Protein ID: Protein_396
Location: 433034..433513 (480 bp)
Type: Others
Protein ID: Protein_398
Location: 433612..433941 (330 bp)
Type: Antitoxin
Protein ID: WP_271253776.1
Location: 433955..434326 (372 bp)
Type: Toxin
Protein ID: WP_271253777.1
Location: 434891..435574 (684 bp)
Type: Others
Protein ID: WP_271253778.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG48_RS01990429290..429940+651WP_271253772.1hypothetical protein-
NMG48_RS01995429959..430198+240WP_271253773.1DUF2281 domain-containing protein-
NMG48_RS02000430282..430563-282WP_271253774.1Txe/YoeB family addiction module toxin-
NMG48_RS02005430550..430834-285WP_271253775.1type II toxin-antitoxin system Phd/YefM family antitoxin-
NMG48_RS02010430967..431698-732Protein_396IS256 family transposase-
NMG48_RS02015431780..432991+1212WP_271251719.1IS256 family transposase-
NMG48_RS02020433034..433513-480Protein_398transposase-
NMG48_RS02025433612..433941-330WP_271253776.1helix-turn-helix transcriptional regulatorAntitoxin
NMG48_RS02030433955..434326-372WP_271253777.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NMG48_RS02035434728..434820+93Protein_401NADH-quinone oxidoreductase subunit C-
NMG48_RS02040434891..435574-684WP_271253778.1Uma2 family endonuclease-
NMG48_RS02050436018..438276+2259WP_271253779.1ABC transporter substrate-binding protein-
NMG48_RS02055438383..439168+786WP_271253780.1cache domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--430967..431599632


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-89)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13874.88 Da        Isoelectric Point: 7.3526

>T252136 WP_271253777.1 NZ_CP101416:c434326-433955 [Pseudanabaena sp. Chao 1811]
VSILPLKSVEWIGSSLDDLKDFPDEVQQVVGYALYIAQCGDKHPSAKPLKGFKGAGVVEIVEDFDGDTYRAVYTIKFADV
VYVLHSFQKKSKQGIATPKQDMDLIEARLKRAKEHYAEHYNKK

Download         Length: 372 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11920.88 Da        Isoelectric Point: 10.4266

>AT252136 WP_271253776.1 NZ_CP101416:c433941-433612 [Pseudanabaena sp. Chao 1811]
MGEEIKVQKSSGNVFADLGLENSDELLVKAELAYKISSIITKLGITQVEAAKLLGIDQPKMSALINGKLSGFSTVRLFRF
LNSLGRDVEIVVKDKPKSRSQARTQVVSR

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References