Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 433612..434326 Replicon chromosome
Accession NZ_CP101416
Organism Pseudanabaena sp. Chao 1811

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NMG48_RS02030 Protein ID WP_271253777.1
Coordinates 433955..434326 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NMG48_RS02025 Protein ID WP_271253776.1
Coordinates 433612..433941 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG48_RS01990 429290..429940 + 651 WP_271253772.1 hypothetical protein -
NMG48_RS01995 429959..430198 + 240 WP_271253773.1 DUF2281 domain-containing protein -
NMG48_RS02000 430282..430563 - 282 WP_271253774.1 Txe/YoeB family addiction module toxin -
NMG48_RS02005 430550..430834 - 285 WP_271253775.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
NMG48_RS02010 430967..431698 - 732 Protein_396 IS256 family transposase -
NMG48_RS02015 431780..432991 + 1212 WP_271251719.1 IS256 family transposase -
NMG48_RS02020 433034..433513 - 480 Protein_398 transposase -
NMG48_RS02025 433612..433941 - 330 WP_271253776.1 helix-turn-helix transcriptional regulator Antitoxin
NMG48_RS02030 433955..434326 - 372 WP_271253777.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NMG48_RS02035 434728..434820 + 93 Protein_401 NADH-quinone oxidoreductase subunit C -
NMG48_RS02040 434891..435574 - 684 WP_271253778.1 Uma2 family endonuclease -
NMG48_RS02050 436018..438276 + 2259 WP_271253779.1 ABC transporter substrate-binding protein -
NMG48_RS02055 438383..439168 + 786 WP_271253780.1 cache domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 430967..431599 632


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-89)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13874.88 Da        Isoelectric Point: 7.3526

>T252136 WP_271253777.1 NZ_CP101416:c434326-433955 [Pseudanabaena sp. Chao 1811]
VSILPLKSVEWIGSSLDDLKDFPDEVQQVVGYALYIAQCGDKHPSAKPLKGFKGAGVVEIVEDFDGDTYRAVYTIKFADV
VYVLHSFQKKSKQGIATPKQDMDLIEARLKRAKEHYAEHYNKK

Download         Length: 372 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11920.88 Da        Isoelectric Point: 10.4266

>AT252136 WP_271253776.1 NZ_CP101416:c433941-433612 [Pseudanabaena sp. Chao 1811]
MGEEIKVQKSSGNVFADLGLENSDELLVKAELAYKISSIITKLGITQVEAAKLLGIDQPKMSALINGKLSGFSTVRLFRF
LNSLGRDVEIVVKDKPKSRSQARTQVVSR

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References