Detailed information of TA system TA025210

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2650780..2651333
• Replicon: chromosome
• Accession: NC_015458
• Organism: Pusillimonas sp. T7-7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: F4GTR6
• Locus tag: PT7_RS12165
• Protein ID: WP_013743558.1
• Coordinates: 2651040..2651333 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: F4GTR5
• Locus tag: PT7_RS12160
• Protein ID: WP_013743557.1
• Coordinates: 2650780..2651052 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PT7_RS12135	2647052..2647831	+	780	WP_013743552.1	succinate dehydrogenase iron-sulfur subunit	-
PT7_RS12145	2648583..2648825	-	243	Protein_2400	DNA repair protein RadC	-
PT7_RS18550	2649036..2649386	-	351	WP_083812444.1	transposase	-
PT7_RS12155	2650009..2650558	+	550	Protein_2402	glycosyltransferase	-
PT7_RS12160	2650780..2651052	+	273	WP_013743557.1	CopG family ribbon-helix-helix protein	Antitoxin
PT7_RS12165	2651040..2651333	+	294	WP_013743558.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PT7_RS19245	2651787..2652050	+	264	WP_013743559.1	hypothetical protein	-
PT7_RS12175	2652382..2652843	-	462	WP_013743561.1	isoprenylcysteine carboxylmethyltransferase family protein	-
PT7_RS12180	2652862..2653572	-	711	WP_013743562.1	Crp/Fnr family transcriptional regulator	-
PT7_RS12185	2653663..2655567	-	1905	WP_013743563.1	cation-translocating P-type ATPase	-
PT7_RS12190	2655640..2655861	-	222	WP_013743564.1	cation transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-95)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-40)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10794.41 Da
• Isoelectric Point: 5.6096

>T25210 WP_013743558.1 NC_015458:2651040-2651333 [Pusillimonas sp. T7-7]
MPQVIVTEGASAGLERCRLFLQTKAPEAARRAGQAIGRQFLLLETAPDIGRPLPEMPELRELVIAFGDSGYVALYHHELT
DDAVYILAFRHQKEVGY

Nucleotide

• Length: 294 bp

>T25210 NC_015458:2651040-2651333 [Pusillimonas sp. T7-7]
ATGCCACAAGTAATCGTCACTGAAGGCGCATCAGCTGGCTTGGAGCGGTGTCGGCTATTCCTGCAAACCAAGGCACCAGA
AGCAGCCAGACGAGCCGGTCAGGCCATTGGGAGGCAATTCCTGCTGCTGGAAACAGCGCCCGACATTGGCCGACCCCTTC
CAGAAATGCCGGAGTTGCGTGAACTGGTTATTGCGTTTGGTGATTCGGGCTACGTCGCCTTGTACCATCACGAATTGACC
GACGACGCGGTGTACATCCTGGCCTTCCGGCATCAGAAAGAGGTGGGCTATTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10547.86 Da
• Isoelectric Point: 8.0852

>AT25210 WP_013743557.1 NC_015458:2650780-2651052 [Pusillimonas sp. T7-7]
MATSLKIDDGLKGRVQHLAGQRRRSPHWIMLEAIRQYVEREEARENFKQEALASWAAYKETGRHLTGQEVRTWLNTWGTD
EEKSVPECHK

Nucleotide

• Length: 273 bp

>AT25210 NC_015458:2650780-2651052 [Pusillimonas sp. T7-7]
ATGGCAACATCTCTCAAAATCGACGATGGCCTGAAAGGCCGTGTCCAGCATCTGGCTGGCCAGCGCCGCCGCTCGCCGCA
CTGGATCATGCTCGAAGCCATTCGGCAGTACGTCGAGCGCGAGGAAGCACGAGAGAACTTCAAACAGGAAGCCTTGGCGT
CCTGGGCGGCTTACAAGGAAACAGGCCGCCACCTGACCGGCCAGGAAGTTCGTACTTGGCTGAACACCTGGGGCACCGAT
GAGGAAAAGTCAGTGCCAGAATGCCACAAGTAA

Structures

Toxin

• AlphaFold DB: F4GTR6

Antitoxin

• AlphaFold DB: F4GTR5