Detailed information of TA system TA025209

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 1562531..1563127
• Replicon: chromosome
• Accession: NC_015458
• Organism: Pusillimonas sp. T7-7

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: F4GVF3
• Locus tag: PT7_RS07000
• Protein ID: WP_013742513.1
• Coordinates: 1562789..1563127 (+)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: F4GVF2
• Locus tag: PT7_RS06995
• Protein ID: WP_013742512.1
• Coordinates: 1562531..1562761 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (4-108)

Antitoxin

• SpoVT-AbrB domain (6-50)

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12337.18 Da
• Isoelectric Point: 8.4957

>T25209 WP_013742513.1 NC_015458:1562789-1563127 [Pusillimonas sp. T7-7]
MNKRYTPDTGDIIHLHFDLPGSSTESSYKPALVLSPMAYNKKTGLVVCCAITNDIKGYPFEVQVQSEQPLAVLSDQVKSI
DWAHTRISQHGRVNAAELAQVRAKLLALISKT

Nucleotide

• Length: 339 bp

>T25209 NC_015458:1562789-1563127 [Pusillimonas sp. T7-7]
ATGAACAAGCGCTATACGCCAGATACCGGCGACATCATCCACCTGCACTTCGACCTGCCTGGCAGCAGTACCGAAAGCAG
CTATAAGCCCGCATTGGTGCTCAGCCCCATGGCCTACAATAAAAAAACCGGGCTTGTGGTCTGTTGCGCCATCACAAACG
ATATCAAGGGCTACCCATTTGAAGTTCAAGTTCAATCCGAGCAGCCTCTGGCCGTGCTGTCGGACCAGGTCAAAAGCATA
GATTGGGCCCATACCCGGATCAGCCAGCATGGCCGAGTCAACGCCGCCGAACTAGCACAAGTGCGCGCCAAGCTGCTGGC
CCTGATTTCCAAGACCTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8371.79 Da
• Isoelectric Point: 9.8654

>AT25209 WP_013742512.1 NC_015458:1562531-1562761 [Pusillimonas sp. T7-7]
MRGVIKKWGNSAAIRLPSSMLKSLKLSADDIVELRLERGTIVIQPVRSEEYLLGQLLSGIKPKNIHPEIDFGAASD

Nucleotide

• Length: 231 bp

>AT25209 NC_015458:1562531-1562761 [Pusillimonas sp. T7-7]
ATGCGCGGTGTAATCAAAAAATGGGGTAATAGCGCTGCGATACGCCTGCCCTCATCCATGCTGAAATCGCTGAAGCTCAG
CGCTGACGACATCGTGGAACTTCGGCTCGAGCGCGGCACGATAGTGATACAGCCCGTACGCTCCGAAGAATATCTGCTTG
GGCAATTGTTAAGCGGCATCAAGCCAAAGAACATACATCCTGAAATAGATTTTGGCGCAGCCAGCGACTAA

Structures

Toxin

• AlphaFold DB: F4GVF3

Antitoxin

• AlphaFold DB: F4GVF2