Detailed information of TA system TA025196

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virT-relB/YafQ-DinJ
• Location: 954983..955526
• Replicon: chromosome
• Accession: NC_015431
• Organism: Mycoplasma mycoides subsp. capri LC str. 95010

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: MLC_RS04095
• Protein ID: WP_013729866.1
• Coordinates: 955248..955526 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MLC_RS04090
• Protein ID: WP_013729865.1
• Coordinates: 954983..955255 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MLC_RS04080	950749..953823	-	3075	WP_013729863.1	hypothetical protein	-
MLC_RS04085	954193..954765	+	573	WP_013729864.1	Fic family protein	-
MLC_RS04090	954983..955255	+	273	WP_013729865.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MLC_RS04095	955248..955526	+	279	WP_013729866.1	type II toxin-antitoxin system YafQ family toxin	Toxin
MLC_RS04100	955705..956790	-	1086	WP_013729867.1	DUF871 family protein	-
MLC_RS04105	956792..958180	-	1389	WP_013729868.1	glycoside hydrolase family 1 protein	-
MLC_RS04110	958173..959051	-	879	WP_013729869.1	ROK family protein	-
MLC_RS04115	959053..959511	-	459	WP_011167001.1	PTS sugar transporter subunit IIA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-79)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10903.98 Da
• Isoelectric Point: 10.0434

>T25196 WP_013729866.1 NC_015431:955248-955526 [Mycoplasma mycoides subsp. capri LC str. 95010]
MIRYTILTTTKFIKDLKLAKKQNKDLEKLDIIINKLKNDEILDKKYKDHQLTGKYEGYRECHIEPDLLIYKKEKKDLLLV
LFRLGSHSKIL

Nucleotide

• Length: 279 bp

>T25196 NC_015431:955248-955526 [Mycoplasma mycoides subsp. capri LC str. 95010]
ATGATTAGGTACACAATACTTACTACAACAAAATTTATTAAAGATTTGAAATTAGCTAAAAAACAAAATAAAGATTTAGA
AAAACTTGACATAATTATTAATAAGTTAAAAAATGATGAAATATTAGATAAAAAATATAAAGATCATCAACTTACTGGTA
AATATGAAGGCTATAGAGAATGTCATATAGAGCCTGATTGACTTTTAATTTATAAAAAGGAGAAAAAAGATCTTCTTTTA
GTACTTTTTAGGTTGGGTTCTCACTCTAAAATACTCTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10424.80 Da
• Isoelectric Point: 4.4569

>AT25196 WP_013729865.1 NC_015431:954983-955255 [Mycoplasma mycoides subsp. capri LC str. 95010]
VKTTNVNIKMDPEIKKQASLLFKEFGMTMSSAINLFVRTAIEQNDIPFEYDREITNKETLEAFEEGERLLADKNAKRYSS
FKEILDSLDD

Nucleotide

• Length: 273 bp

>AT25196 NC_015431:954983-955255 [Mycoplasma mycoides subsp. capri LC str. 95010]
GTGAAAACAACAAATGTAAACATTAAGATGGATCCTGAAATTAAAAAACAGGCTAGTTTGCTATTTAAAGAATTTGGCAT
GACCATGTCTTCTGCTATTAACCTATTTGTAAGAACTGCTATTGAACAAAACGACATTCCATTTGAATATGATAGAGAGA
TAACTAACAAAGAAACTCTAGAAGCTTTTGAAGAAGGTGAACGTCTTTTAGCTGATAAAAATGCAAAACGTTACTCAAGT
TTTAAAGAAATATTAGACTCTTTAGATGATTAG