Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3266524..3267801 Replicon chromosome
Accession NC_015381
Organism Burkholderia gladioli BSR3

Toxin (Protein)


Gene name vapC Uniprot ID F2LCV2
Locus tag BGLA_RS14195 Protein ID WP_013698800.1
Coordinates 3266524..3267108 (-) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BGLA_RS14200 Protein ID WP_013698801.1
Coordinates 3267211..3267801 (-) Length 197 a.a.

Genomic Context

BGLA_RS14165BGLA_RS14170BGLA_RS38770BGLA_RS42975BGLA_RS42450BGLA_RS14195BGLA_RS14200BGLA_RS14205BGLA_RS14210BGLA_RS14215BGLA_RS14220
Location: 3262022..3262438 (417 bp)
Type: Others
Protein ID: WP_052307286.1
Location: 3262562..3263524 (963 bp)
Type: Others
Protein ID: WP_013698797.1
Location: 3263678..3264484 (807 bp)
Type: Others
Protein ID: WP_013698798.1
Location: 3264889..3265626 (738 bp)
Type: Others
Protein ID: WP_044274442.1
Location: 3265646..3265801 (156 bp)
Type: Others
Protein ID: WP_160167523.1
Location: 3266524..3267108 (585 bp)
Type: Toxin
Protein ID: WP_013698800.1
Location: 3267211..3267801 (591 bp)
Type: Antitoxin
Protein ID: WP_013698801.1
Location: 3267958..3268221 (264 bp)
Type: Others
Protein ID: WP_013698802.1
Location: 3268288..3268725 (438 bp)
Type: Others
Protein ID: WP_013698803.1
Location: 3268769..3270784 (2016 bp)
Type: Others
Protein ID: WP_013698804.1
Location: 3270778..3271206 (429 bp)
Type: Others
Protein ID: WP_013698805.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BGLA_RS141653262022..3262438+417WP_052307286.1DUF302 domain-containing protein-
BGLA_RS141703262562..3263524-963WP_013698797.1AraC family transcriptional regulator-
BGLA_RS387703263678..3264484-807WP_013698798.1lytic transglycosylase domain-containing protein-
BGLA_RS429753264889..3265626-738WP_044274442.1hypothetical protein-
BGLA_RS424503265646..3265801-156WP_160167523.1hypothetical protein-
BGLA_RS141953266524..3267108-585WP_013698800.1HD domain-containing proteinToxin
BGLA_RS142003267211..3267801-591WP_013698801.1helix-turn-helix domain-containing proteinAntitoxin
BGLA_RS142053267958..3268221-264WP_013698802.1PAAR domain-containing protein-
BGLA_RS142103268288..3268725-438WP_013698803.1hypothetical protein-
BGLA_RS142153268769..3270784-2016WP_013698804.1VC_2705 family sodium/solute symporter-
BGLA_RS142203270778..3271206-429WP_013698805.1DUF4212 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(8-180)

Antitoxin

Cro/C1-type helix-turn-helix domain

(27-73)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21569.39 Da        Isoelectric Point: 5.1694

>T25182 WP_013698800.1 NC_015381:c3267108-3266524 [Burkholderia gladioli BSR3]
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAVERRDLLRLGETLDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFVYAFNLSY
GQAHTRKVPALQRFRERLDEATRERMARAGGPSG

Download         Length: 585 bp

>T25182 NC_015381:c3267108-3266524 [Burkholderia gladioli BSR3]
ATGGACGACGCGTTGATCGACGCACGACTGGATTTCCTGCGCGGCTGCGAGCGCCTGAAGGATGTGCTGCGCAGCGGCCA
TACCTCGGGCGGCCGCCGCGAGAGCACGGCCGAGCACAGCTGGCGGCTCGCGCTGATGGCGATGGTGCTGATGGATCAAT
TGGGCGAGGTCGACCCCGGCAGGGTGCTCGAGCTCTGCCTGGTGCATGACCTGGGCGAGGCGCTGGGCGGCGACGTGCCG
GCGCCCGAGCAGGCCCCGGGCAGCGACAAGGATGCCGTCGAGCGACGCGATCTGCTGCGCCTCGGCGAAACGCTCGATGC
GCCGATGCGCGAGAGGATCGTCGCGTTGTGGGACGAGTATGCGCGGGCGGCCACGCCGGAAGCGCGCGCGGTGAAGGCGC
TCGACAAGATCGAGACGATCCTGCAGCACACGCAGGGCGAGAATCCGCCCGATTTCGTCTATGCGTTCAATCTCTCGTAT
GGGCAGGCGCATACCCGCAAGGTGCCGGCGCTGCAGCGGTTTCGCGAGCGCCTCGACGAGGCGACGCGCGAGCGGATGGC
CCGTGCTGGCGGGCCTTCGGGCTGA

Antitoxin


Download         Length: 197 a.a.        Molecular weight: 21534.47 Da        Isoelectric Point: 8.7083

>AT25182 WP_013698801.1 NC_015381:c3267801-3267211 [Burkholderia gladioli BSR3]
MKPISSNQATITPLPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDS
AADRALERLVSHHTRPVHLVCDLTHRLLACSTPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWHDHPAPSIEF
DTGSNDSPQVPIRASRCRWTRFTLSDGTLARLVETL

Download         Length: 591 bp

>AT25182 NC_015381:c3267801-3267211 [Burkholderia gladioli BSR3]
ATGAAACCGATATCGTCGAACCAGGCAACGATCACGCCCTTGCCGCCGTCCGCGCTGGCCTGTTCGCCGGGCGCGAGCTT
GCGTCGATGGCGCACGCTGCGCCGGATCAAGCAGGAACATGCGGCGGCGCTGTTCGGCGTATCGCAGTCGACGATATCGC
GCTGGGAAGCCGGCACCCAGGCGGTGTCGCACGAGGAACTGCGGCGCATCGAGGCCTGCTTGTCGGCGCGCCTCGACTCG
GCGGCGGATCGCGCCCTCGAGCGCCTCGTCAGCCATCACACCCGTCCCGTTCATCTCGTCTGCGACCTCACGCACCGGCT
GCTGGCCTGCTCCACGCCGCGAGCCGCGGAGTTCGCGGCGCCGCTGTCGTCGCTGATGGGCGCGTCGCTCTGGCCGTTCG
CGACGGCCGAGATCGTGGCGCGCGAGCAGTCCTTGCGCGATGCGGGCTGGCACGATCATCCGGCACCCTCGATCGAATTC
GATACCGGGTCCAACGACTCGCCGCAGGTGCCGATTCGTGCGAGCCGCTGCCGCTGGACGCGTTTCACCTTGTCCGACGG
GACACTGGCGCGCCTGGTCGAAACGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBF2LCV2

Antitoxin

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Source
ID
Structure
No matching records found

References