Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3436424..3436658 | Replicon | chromosome |
| Accession | NZ_CP101292 | ||
| Organism | Escherichia coli strain 2003-3014 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3436425..3436528 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3436424..3436658 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMK58_RS17900 | 3433622..3434431 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| NMK58_RS17905 | 3434488..3434682 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| NMK58_RS17910 | 3434675..3434863 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 3434681..3434859 | - | 179 | NuclAT_1 | - | - |
| - | 3434681..3434859 | - | 179 | NuclAT_1 | - | - |
| - | 3434681..3434859 | - | 179 | NuclAT_1 | - | - |
| - | 3434681..3434859 | - | 179 | NuclAT_1 | - | - |
| NMK58_RS17915 | 3434970..3435251 | + | 282 | WP_001443927.1 | excisionase | - |
| NMK58_RS17920 | 3435217..3436293 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3436424..3436658 | + | 235 | - | - | Antitoxin |
| - | 3436425..3436528 | - | 104 | - | - | Toxin |
| NMK58_RS17925 | 3436686..3437027 | - | 342 | WP_000976492.1 | YebY family protein | - |
| NMK58_RS17930 | 3437040..3437912 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| NMK58_RS17935 | 3437916..3438290 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| NMK58_RS17940 | 3438429..3438659 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| NMK58_RS17945 | 3438761..3439417 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| NMK58_RS17950 | 3439441..3440103 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 3380114..3442160 | 62046 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T251811 NZ_CP101292:c3436528-3436425 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT251811 NZ_CP101292:3436424-3436658 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
