Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 2877390..2877964 Replicon chromosome
Accession NZ_CP101283
Organism Phenylobacterium sp. LH3H17

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag M9M90_RS14100 Protein ID WP_254833854.1
Coordinates 2877632..2877964 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag M9M90_RS14095 Protein ID WP_254833853.1
Coordinates 2877390..2877632 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9M90_RS14070 (M9M90_14070) 2872580..2873923 - 1344 WP_254833848.1 dicarboxylate/amino acid:cation symporter -
M9M90_RS14075 (M9M90_14075) 2874031..2874528 - 498 WP_254833849.1 hypothetical protein -
M9M90_RS14080 (M9M90_14080) 2874670..2875662 + 993 WP_254833850.1 ABC transporter ATP-binding protein -
M9M90_RS14085 (M9M90_14085) 2875666..2876496 + 831 WP_254833851.1 hypothetical protein -
M9M90_RS14090 (M9M90_14090) 2876501..2877304 + 804 WP_254833852.1 ABC-2 family transporter protein -
M9M90_RS14095 (M9M90_14095) 2877390..2877632 + 243 WP_254833853.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
M9M90_RS14100 (M9M90_14100) 2877632..2877964 + 333 WP_254833854.1 endoribonuclease MazF Toxin
M9M90_RS14105 (M9M90_14105) 2877970..2878977 - 1008 WP_254833855.1 nitronate monooxygenase family protein -
M9M90_RS14110 (M9M90_14110) 2879116..2880537 + 1422 WP_254833856.1 methylmalonyl-CoA mutase family protein -
M9M90_RS14115 (M9M90_14115) 2880534..2882684 + 2151 WP_254833857.1 methylmalonyl-CoA mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-107)

Antitoxin

Antitoxin PemI-like

(2-80)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12091.12 Da        Isoelectric Point: 9.1367

>T251790 WP_254833854.1 NZ_CP101283:2877632-2877964 [Phenylobacterium sp. LH3H17]
VPDYVPDAGHIVWLEFDPQAGHEQAGHRPALVLSAARYNRLRGMMLCCPMTSRIKGYVFEVVASDDPPSVILSDQVKSLD
WRARRAIRKGSVAPAILAEVKAKIAALLQL

Download         Length: 333 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8853.02 Da        Isoelectric Point: 4.3417

>AT251790 WP_254833853.1 NZ_CP101283:2877390-2877632 [Phenylobacterium sp. LH3H17]
VRVQIKKWGNSASVRIPSSVMAAADLTVDQAVDVREEGGRVVIEPVRAPKYDLDQMLDRMTPDTFPQDVDFGPPVGQEAW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References